The detail information of Muscular dystrophy
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: unknown

Mode of inheritance: -

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB67 Cavalier King Charles Spaniel 30.5-33 cm 5.9-8.2 kg United Kingdom (England)
CB111 German Short-Haired Pointer 58.4-63.5 cm (male), 53.3-58.4 cm (female) 24.9-31.8 kg (male), 20.4-27.2 kg (female) Germany
CB116 Golden Retriever 58.4-61 cm (male), 54.6-57.2 cm (female) 29.5-34 kg (male), 24.9-29.5 kg (female) United Kingdom (Scotland)
CB118 Grand Basset Griffon Vendeen 39.4-45.7 cm 18.1-20.4 kg France
CB132 Irish Terrier 45.7 cm 12.2 kg (male), 11.3 kg (female) Ireland
CB147 Labrador Retriever 57.2-62.2 cm (male), 54.6-59.7 cm (female) 29.5-36.3 kg (male), 24.9-31.8 kg (female) Canada, United Kingdom (England)
CB161 Miniature Schnauzer 30.5-35.6 cm 5-9.1 kg Germany
CB179 Pembroke Welsh Corgi 25.4-30.5 cm up to 13.6 kg (male), up to 12.7 kg (female) United Kingdom(Wales)
CB202 American Rat Terrier 25.4-33 cm (miniature), 33-45.7 cm (standard) 4.5-11.3 kg United States
CB205 Rottweiler 61-68.6 cm (male), 55.9-63.5 cm (female) 49.9-59 kg (male), 34.9-49.9 kg (female) Germany
CB210 Samoyed 53.3-59.7 cm (male), 48.3-53.3 cm (female) 20.4-29.5 kg (male), 15.9-22.7 kg (female) Russia
CB252 Weimaraner 63.5-68.6 cm (male), 58.4-63.5 cm (female) 31.8-40.8 kg (male), 24.9-34 kg (female) Germany
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Salvadori,C.,Vattemi,G.,Guglielmi,V.,Marini,M.,Tomelleri,G.,Cantile,C.: :
Protein expression of canine and feline muscular dystrophies. Top Companion Anim Med :100500, 2020.
Pubmed reference: 33249241 . DOI: 10.1016/j.tcam.2020.100500 .
2011 Kornegay,JN.,Bogan,JR.,Bogan,DJ.,Childers,MK.,Grange,RW.: :
Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements. Methods Mol Biol 709:105-23, 2011.
Pubmed reference: 21194024 . DOI: 10.1007/978-1-61737-982-6_7 .
2005 Shelton,GD.,Engvall,E.: :
Canine and feline models of human inherited muscle diseases. Neuromuscul Disord 15:127-38, 2005.
Pubmed reference: 15694134 . DOI: 10.1016/j.nmd.2004.10.019 .
2002 Shelton,G.D.,Engvall,E.: :
Muscular dystrophies and other inherited myopathies Veterinary Clinics of North America - Small Animal Practice 32:103-+, 2002.
2000 Klopp,L.S.,Smith,B.F.: :
Autosomal recessive muscular dystrophy in Labrador retrievers Compendium on Continuing Education for the Practicing Veterinarian 22:121-+, 2000.
1998 Hanson,S.M.,Smith,M.O.,Walker,T.L.,Shelton,G.D.: :
Juvenile-onset distal myopathy in rottweiler dogs Journal of Veterinary Internal Medicine 12:103-108, 1998.
Pubmed reference: 9560767 .
1997 Howell,J.M.,Fletcher,S.,Kakulas,B.A.,Ohara,M.,Lochmuller,H.,Karpati,G.: :
Use of the dog model for duchenne muscular dystrophy in gene therapy trials Neuromuscular Disorders 7:325-328, 1997.
Pubmed reference: 9267846 .
1996 Bartlett,R.J.,Winand,N.J.,Secore,S.L.,Singer,J.T.,Fletcher,S.,Wilton,S.,Bogan,D.J.,Metcalfbogan,J.R.,Bartlett,W.T.,Howell,J.M.,Cooper,B.J.,Kornegay,J.N.: :
Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs American Journal of Veterinary Research 57:650-654, 1996.
Pubmed reference: 8723876 .
1994 Gorospe,J.R.M.,Tharp,M.D.,Hinckley,J.,Kornegay,J.N.,Hoffman,E.P.: :
A Role for Mast Cells in the Progression of Duchenne Muscular Dystrophy - Correlations in Dystrophin-Deficient Humans, Dogs, and Mice Journal of the Neurological Sciences 122:44-56, 1994.
Pubmed reference: 8195802 .
1994 Kornegay,J.N.,Sharp,N.J.H.,Schueler,R.O.,Betts,C.W.: :
Tarsal joint contracture in dogs with golden retriever muscular dystrophy Laboratory Animal Science 44:331-333, 1994.
Pubmed reference: 7983843 .
1994 Pacioretty,L.M.,Cooper,B.J.,Gilmour,R.F.: :
Reduction of the transient outward potassium current in canine X-linked muscular dystrophy Circulation 90:1350-1356, 1994.
Pubmed reference: 8087945 .
1994 Prattis,S.M.,Horton,S.B.,Vancamp,S.D.,Kornegay,J.N.: :
Immunohistochemical Detection of Neural Cell Adhesion Molecule and Laminin in X-Linked Dystrophic Dogs and Mdx Mice Journal of Comparative Pathology 110:253-266, 1994.
Pubmed reference: 8040390 .
1994 Wilson,L.A.,Cooper,B.J.,Dux,L.,Dubowitz,V.,Sewry,C.A.: :
Expression of utrophin (dystrophin-related protein) during regeneration and maturation of skeletal muscle in canine X- linked muscular dystrophy Neuropathology and Applied Neurobiology 20:359-367, 1994.
Pubmed reference: 7808586 .
1994 Wilson,L.A.,Dux,L.,Cooper,B.J.,Dubowitz,V.,Sewry,C.A.: :
Experimental Regeneration in Canine Muscular Dystrophy .2. Expression of Myosin Heavy Chain Isoforms Neuromuscular Disorders 4:25-37, 1994.
Pubmed reference: 7513568 .
1993 Anderson,J.E.,Kakulas,B.A.,Jacobsen,P.F.,Johnsen,R.D.,Kornegay,J.N.,Grounds,M.D.: :
Comparison of Basic Fibroblast Growth Factor in X-Linked Dystrophin-Deficient Myopathies of Human, Dog and Mouse Growth Factors 9:107-121, 1993.
Pubmed reference: 8217214 .
1993 Prattis,S.M.,Gebhart,D.H.,Dickson,G.,Watt,D.J.,Kornegay,J.N.: :
Magnetic Affinity Cell Sorting (MACS) Separation and Flow Cytometric Characterization of Neural Cell Adhesion Molecule- Positive, Cultured Myogenic Cells from Normal and Dystrophic Dogs Experimental Cell Research 208:453-464, 1993.
Pubmed reference: 8375474 . DOI: 10.1006/excr.1993.1267 .
1992 Sharp,N.J.H.,Kornegay,J.N.,Vancamp,S.D.,Herbstreith,M.H.,Secore,S.L.,Kettle,S.,Hung,W.Y.,Constantinou,C.D.,Dykstra,M.J.,Roses,A.D.,Bartlett,R.J.: :
An Error in Dystrophin Messenger RNA Processing in Golden Retriever Muscular Dystrophy, an Animal Homologue of Duchenne Muscular Dystrophy Genomics 13:115-121, 1992.
Pubmed reference: 1577476 .
1992 Valentine,B.A.,Winand,N.J.,Pradhan,D.,Moise,N.S.,Delahunta,A.,Kornegay,J.N.,Cooper,B.J.: :
Canine X-Linked Muscular Dystrophy as an Animal Model of Duchenne Muscular Dystrophy - A Review American Journal of Medical Genetics 42:352-356, 1992.
Pubmed reference: 1536178 . DOI: 10.1002/ajmg.1320420320 .
1991 Mccully,K.,Giger,U.,Argov,Z.,Valentine,B.,Cooper,B.,Chance,B.,Bank,W.: :
Canine X-Linked Muscular Dystrophy Studied with Invivo Phosphorus Magnetic Resonance Spectroscopy Muscle & Nerve 14:1091-1098, 1991.
Pubmed reference: 1745283 . DOI: 10.1002/mus.880141109 .
1991 Mehta,J.R.,Braund,K.G.,Hegreberg,G.A.,Thukrall,V.: :
Lipid Fluidity and Composition of the Erythrocyte Membrane from Healthy Dogs and Labrador Retrievers with Hereditary Muscular Dystrophy Neurochemical Research 16:129-135, 1991.
Pubmed reference: 1908955 .
1991 Valentine,B.A.,Chandler,S.K.,Cummings,J.F.,Cooper,B.J.: :
Invitro Characteristics of Normal and Dystrophic Skeletal Muscle from Dogs American Journal of Veterinary Research 52:104-107, 1991.
Pubmed reference: 2021236 .
1990 Cooper,B.J.,Gallagher,E.A.,Smith,C.A.,Valentine,B.A.,Winand,N.J.: :
Mosaic Expression of Dystrophin in Carriers of Canine X-Linked Muscular Dystrophy Laboratory Investigation 62:171-178, 1990.
Pubmed reference: 2406503 .
1989 Valentine,B.A.,Cummings,J.F.,Cooper,B.J.: :
Development of Duchenne-Type Cardiomyopathy - Morphologic Studies in a Canine Model American Journal of Pathology 135:671-678, 1989.
Pubmed reference: 2679113 .
1989 Valentine,B.A.,Kornegay,J.N.,Cooper,B.J.: :
Clinical Electromyographic Studies of Canine X-Linked Muscular Dystrophy American Journal of Veterinary Research 50:2145-2147, 1989.
Pubmed reference: 2610444 .