The detail information of Dermatitis, atopic
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: unknown

Mode of inheritance: -

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: Canine atopic dermatitis (CAD)

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB48 German Boxer 58.4-63.5 cm (male), 54.6-59.7 cm (female) 29.5-36.3 kg (male), females are about 6.8 kg less than male Germany
CB58 English Bulldog 35.6-38.1 cm 22.7 kg (male), 18.1 kg (female) United Kingdom (England)
CB110 German Shepherd Dog 61-66 cm (male), 55.9-61 cm (female) 29.5-40.8 kg (male), 22.7-31.8 kg (female) Germany
CB147 Labrador Retriever 57.2-62.2 cm (male), 54.6-59.7 cm (female) 29.5-36.3 kg (male), 24.9-31.8 kg (female) Canada, United Kingdom (England)
CB196 Pug 25.4-33 cm 6.4-8.2 kg China
CB255 West Highland White Terrier 27.9 cm (male). 25.4 cm, female 6.8-9.1 kg United Kingdom (Scotland)
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Marsella,R.: :
Advances in our understanding of canine atopic dermatitis. Vet Dermatol :, 2021.
Pubmed reference: 33891338 . DOI: 10.1111/vde.12965 .
2020 Combarros,D.,Cadiergues,M.C.,Simon,M.: :
Update on canine filaggrin: a review. Vet Q :1-9, 2020.
Pubmed reference: 32308144 . DOI: 10.1080/01652176.2020.1758357 .
2020 Tanaka,K.,Yamamoto-Fukuda,M.,Takizawa,T.,Shimakura,H.,Sakaguchi,M.: :
Association analysis of non-synonymous polymorphisms of interleukin-4 receptor-α and interleukin-13 genes in canine atopic dermatitis. J Vet Med Sci :, 2020.
Pubmed reference: 32669513 . DOI: 10.1292/jvms.20-0301 .
2020 Tengvall,K.,Bergvall,K.,Olsson,M.,Ardesjö-Lundgren,B.,Farias,F.H.G.,Kierczak,M.,Hedhammar,Å.,Lindblad-Toh,K.,Andersson,G.: :
Transcriptomes from German shepherd dogs reveal differences in immune activity between atopic dermatitis affected and control skin. Immunogenetics 72:315-323, 2020.
Pubmed reference: 32556497 . DOI: 10.1007/s00251-020-01169-3 .
2019 Agler,C.S.,Friedenberg,S.,Olivry,T.,Meurs,K.M.,Olby,N.J.: :
Genome-wide association analysis in West Highland White Terriers with atopic dermatitis. Vet Immunol Immunopathol 209:1-6, 2019.
Pubmed reference: 30885300 . DOI: 10.1016/j.vetimm.2019.01.004 .
2019 Harvey,N.D.,Shaw,S.C.,Craigon,P.J.,Blott,S.C.,England,G.C.W.: :
Environmental risk factors for canine atopic dermatitis: a retrospective large-scale study in Labrador and golden retrievers. Vet Dermatol 30:396-e119, 2019.
Pubmed reference: 31407839 . DOI: 10.1111/vde.12782 .
2019 Summers,J.F.,O'Neill,D.G.,Church,D.,Collins,L.,Sargan,D.,Brodbelt,D.C.: :
Health-related welfare prioritisation of canine disorders using electronic health records in primary care practice in the UK. BMC Vet Res 15:163, 2019.
Pubmed reference: 31118035 . DOI: 10.1186/s12917-019-1902-0 .
2017 Martel,B.C.,Lovato,P.,Bäumer,W.,Olivry,T.: :
Translational Animal Models of Atopic Dermatitis for Preclinical Studies. Yale J Biol Med 90:389-402, 2017.
Pubmed reference: 28955179 .
2016 Asahina,R.,Maeda,S.: :
A review of the roles of keratinocyte-derived cytokines and chemokines in the pathogenesis of atopic dermatitis in humans and dogs. Vet Dermatol :, 2016.
Pubmed reference: 27426268 . DOI: 10.1111/vde.12351 .
2016 Bruet,V.,Dumon,H.,Bourdeau,P.,Desfontis,J.C.,Martin,L.: :
Prospective pilot study to detect dogs with non food-induced canine atopic dermatitis using Fourier transform infrared spectroscopy. Vet Dermatol 27:356-e89, 2016.
Pubmed reference: 27500559 . DOI: 10.1111/vde.12365 .
2016 Fujimura,M.,Ishimaru,H.: :
Rush sublingual immunotherapy in canine atopic dermatitis: a prospective pilot study. Pol J Vet Sci 19:3-6, 2016.
Pubmed reference: 27096781 . DOI: 10.1515/pjvs-2016-0001 .
2016 Hauck,V.,Hügli,P.,Meli,M.L.,Rostaher,A.,Fischer,N.,Hofmann-Lehmann,R.,Favrot,C.: :
Increased numbers of FoxP3-expressing CD4+ CD25+ regulatory T cells in peripheral blood from dogs with atopic dermatitis and its correlation with disease severity. Vet Dermatol 27:26-e9, 2016.
Pubmed reference: 26748886 . DOI: 10.1111/vde.12279 .
2016 Kim,H.J.,Cronin,M.,Ahrens,K.,Papastavros,V.,Santoro,D.,Marsella,R.: :
A comparative study of epidermal tight junction proteins in a dog model of atopic dermatitis. Vet Dermatol 27:40-e11, 2016.
Pubmed reference: 26663564 . DOI: 10.1111/vde.12276 .
2016 Majewska,A.,Gajewska,M.,Dembele,K.,Maciejewski,H.,Prostek,A.,Jank,M.: :
Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis. BMC Vet Res 12:174, 2016.
Pubmed reference: 27553600 . DOI: 10.1186/s12917-016-0805-6 .
2016 Mazrier,H.,Vogelnest,L.J.,Thomson,P.C.,Taylor,R.M.,Williamson,P.: :
Canine atopic dermatitis: breed risk in Australia and evidence for a susceptible clade. Vet Dermatol 27:167-e42, 2016.
Pubmed reference: 27188769 . DOI: 10.1111/vde.12317 .
2016 Pierezan,F.,Olivry,T.,Paps,J.S.,Lawhon,S.D.,Wu,J.,Steiner,J.M.,Suchodolski,J.S.,RodriguesHoffmann,A.: :
The skin microbiome in allergen-induced canine atopic dermatitis. Vet Dermatol :, 2016.
Pubmed reference: 27485242 . DOI: 10.1111/vde.12366 .
2016 Sakamoto,M.,Asahina,R.,Kamishina,H.,Maeda,S.: :
Transcription of thymic stromal lymphopoietin via Toll-like receptor 2 in canine keratinocytes: a possible association of Staphylococcus spp. in the deterioration of allergic inflammation in canine atopic dermatitis. Vet Dermatol :, 2016.
Pubmed reference: 27018172 . DOI: 10.1111/vde.12301 .
2016 Saridomichelakis,M.N.,Olivry,T.: :
An update on the treatment of canine atopic dermatitis. Vet J 207:29-37, 2016.
Pubmed reference: 26586215 . DOI: 10.1016/j.tvjl.2015.09.016 .
2016 Tengvall,K.,Kozyrev,S.,Kierczak,M.,Bergvall,K.,Farias,F.H.,Ardesjö-Lundgren,B.,Olsson,M.,Murén,E.,Hagman,R.,Leeb,T.,Pielberg,G.,Hedhammar,Å.,Andersson,G.,Lindblad-Toh,K.: :
Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs. BMC Genet 17:97, 2016.
Pubmed reference: 27357287 . DOI: 10.1186/s12863-016-0404-3 .
2015 Bizikova,P.,Pucheu-Haston,C.M.,Eisenschenk,M.N.,Marsella,R.,Nuttall,T.,Santoro,D.: :
Review: Role of genetics and the environment in the pathogenesis of canine atopic dermatitis. Vet Dermatol :, 2015.
Pubmed reference: 25703290 . DOI: 10.1111/vde.12198 .
2015 Bizikova,P.,Santoro,D.,Marsella,R.,Nuttall,T.,Eisenschenk,M.N.,Pucheu-Haston,C.M.: :
Review: Clinical and histological manifestations of canine atopic dermatitis. Vet Dermatol :, 2015.
Pubmed reference: 25676252 . DOI: 10.1111/vde.12196 .
2015 Hensel,P.,Santoro,D.,Favrot,C.,Hill,P.,Griffin,C.: :
Canine atopic dermatitis: detailed guidelines for diagnosis and allergen identification. BMC Vet Res 11:196, 2015.
Pubmed reference: 26260508 . DOI: 10.1186/s12917-015-0515-5 .
2015 LeRoy,L.,LePoder,S.,Desquilbet,L.,Perrot,S.,Cavana,P.,Marignac,G.: :
Canine Atopic Dermatitis Diagnostic Criteria: Evaluation of Four Sets of Published Criteria among Veterinary Students. J Vet Med Educ 42:79-84, 2015.
Pubmed reference: 25588943 . DOI: 10.3138/jvme.0414-038R1 .
2015 Mineshige,T.,Kamiie,J.,Sugahara,G.,Yasuno,K.,Aihara,N.,Kawarai,S.,Yamagishi,K.,Shirota,M.,Shirota,K.: :
Expression of Periostin in Normal, Atopic, and Nonatopic Chronically Inflamed Canine Skin. Vet Pathol :, 2015.
Pubmed reference: 25755133 . DOI: 10.1177/0300985815574007 .
2015 Müller,M.R.,Linek,M.,Löwenstein,C.,Röthig,A.,Doucette,K.,Thorstensen,K.,Mueller,R.S.: :
Evaluation of cyclosporine-sparing effects of polyunsaturated fatty acids in the treatment of canine atopic dermatitis. Vet J :, 2015.
Pubmed reference: 26975448 . DOI: 10.1016/j.tvjl.2015.11.012 .
2015 Pucheu-Haston,C.M.,Bizikova,P.,Eisenschenk,M.N.,Santoro,D.,Nuttall,T.,Marsella,R.: :
Review: The role of antibodies, autoantigens and food allergens in canine atopic dermatitis. Vet Dermatol :, 2015.
Pubmed reference: 25728611 . DOI: 10.1111/vde.12201 .
2015 Pucheu-Haston,C.M.,Bizikova,P.,Marsella,R.,Santoro,D.,Nuttall,T.,Eisenschenk,M.N.: :
Review: Lymphocytes, cytokines, chemokines and the T-helper 1-T-helper 2 balance in canine atopic dermatitis. Vet Dermatol 26:124-e32, 2015.
Pubmed reference: 25808535 . DOI: 10.1111/vde.12205 .
2015 Pucheu-Haston,C.M.,Eisenschenk,M.N.,Bizikova,P.,Marsella,R.,Nuttall,T.,Santoro,D.: :
Introduction to the review articles by ICADA on the pathogenesis of atopic dermatitis in dogs. Vet Dermatol 26:77-8, 2015.
Pubmed reference: 25808534 . DOI: 10.1111/vde.12207 .
2015 Pucheu-Haston,C.M.,Santoro,D.,Bizikova,P.,Eisenschenk,M.N.,Marsella,R.,Nuttall,T.: :
Review: Innate immunity, lipid metabolism and nutrition in canine atopic dermatitis. Vet Dermatol :, 2015.
Pubmed reference: 25728538 . DOI: 10.1111/vde.12199 .
2015 Santoro,D.,Marsella,R.,Pucheu-Haston,C.M.,Eisenschenk,M.N.,Nuttall,T.,Bizikova,P.: :
Review: Pathogenesis of canine atopic dermatitis: skin barrier and host-micro-organism interaction. Vet Dermatol :, 2015.
Pubmed reference: 25683702 . DOI: 10.1111/vde.12197 .
2014 Bruet,V.,Lieubeau,B.,Herve,J.,Roussel,A.,Imparato,L.,Desfontis,J.,Bourdeau,P.: :
Increased numbers of peripheral blood CD34+ cells in dogs with canine atopic dermatitis. Vet Dermatol :, 2014.
Pubmed reference: 25537867 . DOI: 10.1111/vde.12191 .
2014 Litzlbauer,P.,Weber,K.,Mueller,R.S.: :
Oral and subcutaneous therapy of canine atopic dermatitis with recombinant feline interferon omega. Cytokine 66:54-9, 2014.
Pubmed reference: 24548425 . DOI: 10.1016/j.cyto.2013.12.001 .
2014 Olivry,T.,Saridomichelakis,M.,Nuttall,T.,Bensignor,E.,Griffin,C.E.,Hill,P.B.: :
Validation of the Canine Atopic Dermatitis Extent and Severity Index (CADESI)-4, a simplified severity scale for assessing skin lesions of atopic dermatitis in dogs. Vet Dermatol :, 2014.
Pubmed reference: 24461108 . DOI: 10.1111/vde.12107 .
2014 Schumann,J.,Basiouni,S.,Gück,T.,Fuhrmann,H.: :
Treating canine atopic dermatitis with unsaturated fatty acids: the role of mast cells and potential mechanisms of action. J Anim Physiol Anim Nutr (Berl) :, 2014.
Pubmed reference: 24628699 . DOI: 10.1111/jpn.12181 .
2013 Dip,R.,Carmichael,J.,Letellier,I.,Strehlau,G.,Roberts,E.,Bensignor,E.,Rosenkrantz,W.: :
Concurrent short-term use of prednisolone with cyclosporine A accelerates pruritus reduction and improvement in clinical scoring in dogs with atopic dermatitis. BMC Vet Res 9:173, 2013.
Pubmed reference: 24004561 . DOI: 10.1186/1746-6148-9-173 .
2013 Fernández-Caldas,E.: :
On mite allergy in dogs and humans. Int Arch Allergy Immunol 160:329-30, 2013.
Pubmed reference: 23172128 . DOI: 10.1159/000343492 .
2013 Jassies-vanderLee,A.,Rutten,V.,Spiering,R.,vanKooten,P.,Willemse,T.,Broere,F.: :
The immunostimulatory effect of CpG oligodeoxynucleotides on peripheral blood mononuclear cells of healthy dogs and dogs with atopic dermatitis. Vet J :, 2013.
Pubmed reference: 24461202 . DOI: 10.1016/j.tvjl.2013.12.016 .
2013 Jung,J.Y.,Nam,E.H.,Park,S.H.,Han,S.H.,Hwang,C.Y.: :
Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis. J Vet Sci 14:199-205, 2013.
Pubmed reference: 23814473 . DOI: 10.4142/jvs.2013.14.2.199 .
2013 Koike,A.,Kano,R.,Nagata,M.,Chen,C.,Hwang,C.Y.,Hasegawa,A.,Kamata,H.: :
Genotyping of Malassezia pachydermatis Isolates from Canine Healthy Skin and Lesional Skin of Atopic Dermatitis in Japan, Korea and Taiwan. J Vet Med Sci :, 2013.
Pubmed reference: 23411408 .
2013 Lancto,C.A.,Torres,S.M.,Hendrickson,J.A.,Martins,K.V.,Rutherford,M.S.: :
Altered expression of antimicrobial peptide genes in the skin of dogs with atopic dermatitis and other inflammatory skin conditions. Vet Dermatol :, 2013.
Pubmed reference: 23701024 . DOI: 10.1111/vde.12034 .
2013 Nuttall,T.: :
The genomics revolution: will canine atopic dermatitis be predictable and preventable? Vet Dermatol 24:10-8.e3-4, 2013.
Pubmed reference: 23331674 . DOI: 10.1111/j.1365-3164.2012.01094.x .
2013 Nuttall,T.,Uri,M.,Halliwell,R.: :
Canine atopic dermatitis - what have we learned? Vet Rec 172:201-7, 2013.
Pubmed reference: 23436599 . DOI: 10.1136/vr.f1134 .
2013 Ognjenovic,J.,Milcic-Matic,N.,Smiljanic,K.,Vuckovic,O.,Burazer,L.,Popovic,N.,Stanic-Vucinic,D.,Velickovic,T.C.: :
Immunoproteomic characterization of Ambrosia artemisiifolia pollen allergens in canine atopic dermatitis. Vet Immunol Immunopathol 155:38-47, 2013.
Pubmed reference: 23830203 . DOI: 10.1016/j.vetimm.2013.06.005 .
2013 Pellicoro,C.,Marsella,R.,Ahrens,K.: :
Pilot study to evaluate the effect of topical dimethicone on clinical signs and skin barrier function in dogs with naturally occurring atopic dermatitis. Vet Med Int 2013:239186, 2013.
Pubmed reference: 23710417 . DOI: 10.1155/2013/239186 .
2013 Prélaud,A.R.,Fuchs,S.,Weber,K.,Winter,G.,Coester,C.,Mueller,R.S.: :
In vitro effects of CpG oligodeoxynucleotides delivered by gelatin nanoparticles on canine peripheral blood mononuclear cells of atopic and healthy dogs - a pilot study. Vet Dermatol :, 2013.
Pubmed reference: 23826658 . DOI: 10.1111/vde.12056 .
2013 Puigdemont,A.,Brazís,P.,Ordeix,L.,Dalmau,A.,Fuertes,E.,Olivar,A.,Pérez,C.,Ravera,I.: :
Efficacy of a new topical cyclosporine A formulation in the treatment of atopic dermatitis in dogs. Vet J :, 2013.
Pubmed reference: 23562341 . DOI: 10.1016/j.tvjl.2013.02.018 .
2013 Santoro,D.,Marsella,R.,Ahrens,K.,Graves,T.K.,Bunick,D.: :
Altered mRNA and protein expression of filaggrin in the skin of a canine animal model for atopic dermatitis. Vet Dermatol 24:329-36, e73, 2013.
Pubmed reference: 23668858 . DOI: 10.1111/vde.12031 .
2013 Tengvall,K.,Kierczak,M.,Bergvall,K.,Olsson,M.,Frankowiack,M.,Farias,F.H.,Pielberg,G.,Carlborg,O.,Leeb,T.,Andersson,G.,Hammarström,L.,Hedhammar,A.,Lindblad-Toh,K.: :
Correction: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis. PLoS Genet 9:, 2013.
Pubmed reference: 23696744 . DOI: 10.1371/annotation/fd6f4425-3d84-4017-a012-a5df6ddee13a .
2013 Tengvall,K.,Kierczak,M.,Bergvall,K.,Olsson,M.,Frankowiack,M.,Farias,F.H.,Pielberg,G.,Carlborg,Ö.,Leeb,T.,Andersson,G.,Hammarström,L.,Hedhammar,Å.,Lindblad-Toh,K.: :
Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis. PLoS Genet 9:e1003475, 2013.
Pubmed reference: 23671420 . DOI: 10.1371/journal.pgen.1003475 .
2012 Campora,L.,Miragliotta,V.,Ricci,E.,Cristino,L.,DiMarzo,V.,Albanese,F.,FedericaDellaValle,M.,Abramo,F.: :
Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis. Am J Vet Res 73:988-95, 2012.
Pubmed reference: 22738050 . DOI: 10.2460/ajvr.73.7.988 .
2012 Kovalik,M.,Thoday,K.L.,Evans,H.,Berry,J.,vandenBroek,A.H.,Mellanby,R.J.: :
Short-term prednisolone therapy has minimal impact on calcium metabolism in dogs with atopic dermatitis. Vet J :, 2012.
Pubmed reference: 22277720 . DOI: 10.1016/j.tvjl.2011.12.003 .
2012 Lauber,B.,Molitor,V.,Meury,S.,Doherr,M.G.,Favrot,C.,Tengvall,K.,Bergvall,K.,Leeb,T.,Roosje,P.,Marti,E.: :
Total IgE and allergen-specific IgE and IgG antibody levels in sera of atopic dermatitis affected and non-affected Labrador- and Golden retrievers. Vet Immunol Immunopathol 149:112-8, 2012.
Pubmed reference: 22739207 . DOI: 10.1016/j.vetimm.2012.05.018 .
2012 Marsella,R.,Sousa,C.A.,Gonzales,A.J.,Fadok,V.A.: :
Current understanding of the pathophysiologic mechanisms of canine atopic dermatitis. J Am Vet Med Assoc 241:194-207, 2012.
Pubmed reference: 22765366 . DOI: 10.2460/javma.241.2.194 .
2012 Olivry,T.: :
What can dogs bring to atopic dermatitis research? Chem Immunol Allergy 96:61-72, 2012.
Pubmed reference: 22433372 . DOI: 10.1159/000331884 .
2012 Plager,D.A.,Torres,S.M.,Koch,S.N.,Kita,H.: :
Gene transcription abnormalities in canine atopic dermatitis and related human eosinophilic allergic diseases. Vet Immunol Immunopathol 149:136-42, 2012.
Pubmed reference: 22749291 . DOI: 10.1016/j.vetimm.2012.06.003 .
2012 Plant,J.D.,Gortel,K.,Kovalik,M.,Polissar,N.L.,Neradilek,M.B.: :
Development and validation of the Canine Atopic Dermatitis Lesion Index, a scale for the rapid scoring of lesion severity in canine atopic dermatitis. Vet Dermatol 23:515-e103, 2012.
Pubmed reference: 23140318 . DOI: 10.1111/j.1365-3164.2012.01113.x .
2012 Roque,J.B.,O'Leary,C.A.,Duffy,D.L.,Kyaw-Tanner,M.,Gharahkhani,P.,Vogelnest,L.,Mason,K.,Shipstone,M.,Latter,M.: :
Atopic dermatitis in West Highland white terriers is associated with a 1.3-Mb region on CFA 17. Immunogenetics 64:209-17, 2012.
Pubmed reference: 21989516 . DOI: 10.1007/s00251-011-0577-x .
2012 Theerawatanasirikul,S.,Sailasuta,A.,Thanawongnuwech,R.,Suriyaphol,G.: :
Alterations of keratins, involucrin and filaggrin gene expression in canine atopic dermatitis. Res Vet Sci 93:1287-92, 2012.
Pubmed reference: 22784629 . DOI: 10.1016/j.rvsc.2012.06.005 .
2011 Kovalik,M.,Thoday,KL.,Evans,H.,vandenBroek,AH.,Mellanby,RJ.: :
Prednisolone is associated with an increase in serum insulin but not serum fructosamine concentrations in dogs with atopic dermatitis. Vet J :, 2011.
Pubmed reference: 21745752 . DOI: 10.1016/j.tvjl.2011.06.002 .
2011 Marsella,R.,Olivry,T.,Carlotti,D.N.: :
Current evidence of skin barrier dysfunction in human and canine atopic dermatitis. Vet Dermatol 22:239-48, 2011.
Pubmed reference: 21414049 . DOI: 10.1111/j.1365-3164.2011.00967.x .
2011 Meury,S.,Molitor,V.,Doherr,M.G.,Roosje,P.,Leeb,T.,Hobi,S.,Wilhelm,S.,Favrot,C.: :
Role of the environment in the development of canine atopic dermatitis in Labrador and golden retrievers. Vet Dermatol 22:327-34, 2011.
Pubmed reference: 21251098 . DOI: 10.1111/j.1365-3164.2010.00950.x .
2011 Olivry,T.: :
Is the skin barrier abnormal in dogs with atopic dermatitis? Vet Immunol Immunopathol :, 2011.
Pubmed reference: 21835476 . DOI: 10.1016/j.vetimm.2011.07.014 .
2011 Roque,J.B.,O'Leary,C.A.,Kyaw-Tanner,M.,Duffy,D.L.,Gharahkhani,P.,Vogelnest,L.,Mason,K.,Shipstone,M.: :
PTPN22 polymorphisms may indicate a role for this gene in atopic dermatitis in West Highland white terriers. BMC Res Notes 4:571, 2011.
Pubmed reference: 22208456 . DOI: 10.1186/1756-0500-4-571 .
2011 Salzmann,C.A.,Olivry,T.J.,Nielsen,D.M.,Paps,J.S.,Harris,T.L.,Olby,N.J.: :
Genome-wide linkage study of atopic dermatitis in West Highland White Terriers. BMC Genet 12:37, 2011.
Pubmed reference: 21510878 . DOI: 10.1186/1471-2156-12-37 .
2010 Chervet,L.,Galichet,A.,McLean,W.H.,Chen,H.,Suter,M.M.,Roosje,P.J.,Müller,E.J.: :
Missing C-terminal filaggrin expression, NFkappaB activation and hyperproliferation identify the dog as a putative model to study epidermal dysfunction in atopic dermatitis. Exp Dermatol 19:e343-6, 2010.
Pubmed reference: 20626465 . DOI: 10.1111/j.1600-0625.2010.01109.x .
2010 Favrot,C.,Steffan,J.,Seewald,W.,Picco,F.: :
A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol 21:23-31, 2010.
Pubmed reference: 20187911 . DOI: 10.1111/j.1365-3164.2009.00758.x .
2010 Jaeger,K.,Linek,M.,Power,H.T.,Bettenay,S.V.,Zabel,S.,Rosychuk,R.A.,Mueller,R.S.: :
Breed and site predispositions of dogs with atopic dermatitis: a comparison of five locations in three continents. Vet Dermatol 21:118-22, 2010.
Pubmed reference: 20187918 . DOI: 10.1111/j.1365-3164.2009.00845.x .
2010 Marsella,R.: :
Canine atopic dermatitis: what's new? Compend Contin Educ Vet 32:E1-4, 2010.
Pubmed reference: 20473848 .
2010 Olivry,T.: :
New diagnostic criteria for canine atopic dermatitis. Vet Dermatol 21:123-6, 2010.
Pubmed reference: 20187919 . DOI: 10.1111/j.1365-3164.2009.00776.x .
2010 Olivry,T.,Foster,AP.,Mueller,RS.,McEwan,NA.,Chesney,C.,Williams,HC.: :
Interventions for atopic dermatitis in dogs: a systematic review of randomized controlled trials. Vet Dermatol 21:4-22, 2010.
Pubmed reference: 20187909 . DOI: 10.1111/j.1365-3164.2009.00873.x .
2009 Marsella,R.,Girolomoni,G.: :
Canine models of atopic dermatitis: a useful tool with untapped potential. J Invest Dermatol 129:2351-7, 2009.
Pubmed reference: 19516261 . DOI: 10.1038/jid.2009.98 .
2009 Marsella,R.,Samuelson,D.: :
Unravelling the skin barrier: a new paradigm for atopic dermatitis and house dust mites. Vet Dermatol 20:533-40, 2009.
Pubmed reference: 20178491 . DOI: 10.1111/j.1365-3164.2009.00809.x .
2009 Wood,S.H.,Clements,D.N.,Ollier,W.E.,Nuttall,T.,McEwan,N.A.,Carter,S.D.: :
Gene expression in canine atopic dermatitis and correlation with clinical severity scores. J Dermatol Sci 55:27-33, 2009.
Pubmed reference: 19394200 . DOI: 10.1016/j.jdermsci.2009.03.005 .
2009 Wood,S.H.,Ke,X.,Nuttall,T.,McEwan,N.,Ollier,W.E.,Carter,S.D.: :
Genome-wide association analysis of canine atopic dermatitis and identification of disease related SNPs. Immunogenetics 61:765-72, 2009.
Pubmed reference: 19838693 . DOI: 10.1007/s00251-009-0402-y .
2008 Keppel,KE.,Campbell,KL.,Zuckermann,FA.,Greeley,EA.,Schaeffer,DJ.,Husmann,RJ.: :
Quantitation of canine regulatory T cell populations, serum interleukin-10 and allergen-specific IgE concentrations in healthy control dogs and canine atopic dermatitis patients receiving allergen-specific immunotherapy. Vet Immunol Immunopathol 123:337-44, 2008.
Pubmed reference: 18423890 . DOI: 10.1016/j.vetimm.2008.02.008 .
2007 Nødtvedt,A.,Guitian,J.,Egenvall,A.,Emanuelson,U.,Pfeiffer,D.U.: :
The spatial distribution of atopic dermatitis cases in a population of insured Swedish dogs. Prev Vet Med 78:210-22, 2007.
Pubmed reference: 17112611 . DOI: 10.1016/j.prevetmed.2006.10.007 .
2006 Breathnach,R.,Donahy,C.,Jones,B.R.,Bloomfield,F.J.: :
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2006 Nødtvedt,A.,Egenvall,A.,Bergvall,K.,Hedhammar,A.: :
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2006 Steffan,J.,Favrot,C.,Mueller,R.: :
A systematic review and meta-analysis of the efficacy and safety of cyclosporin for the treatment of atopic dermatitis in dogs. Vet Dermatol 17:3-16, 2006.
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2006 Tarpataki,N.: :
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2005 Colombo,S.,Hill,PB.,Shaw,DJ.,Thoday,KL.: :
Effectiveness of low dose immunotherapy in the treatment of canine atopic dermatitis: a prospective, double-blinded, clinical study. Vet Dermatol 16:162-70, 2005.
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2005 Hou,CC.,Pemberton,A.,Nuttall,T.,Hill,PB.: :
IgG responses to antigens from Dermatophagoides farinae in healthy and atopic dogs. Vet Immunol Immunopathol 106:121-8, 2005.
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2005 Maeda,S.,Tsukui,T.,Saze,K.,Masuda,K.,Ohno,K.,Tsujimoto,H.,Iwabuchi,S.: :
Production of a monoclonal antibody to canine thymus and activation-regulated chemokine (TARC) and detection of TARC in lesional skin from dogs with atopic dermatitis. Vet Immunol Immunopathol 103:83-92, 2005.
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2005 McEwan,NA.,Kalna,G.,Mellor,D.: :
A comparison of adherence by four strains of Staphylococcus intermedius and Staphylococcus hominis to canine corneocytes collected from normal dogs and dogs suffering from atopic dermatitis. Res Vet Sci 78:193-8, 2005.
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2005 Mueller,R.S.,Fieseler,K.V.,Rosychuk,R.A.,Greenwalt,T.: :
Intradermal testing with the storage mite Tyrophagus putrescentiae in normal dogs and dogs with atopic dermatitis in Colorado. Vet Dermatol 16:27-31, 2005.
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2005 Mueller,RS.,Fettman,MJ.,Richardson,K.,Hansen,RA.,Miller,A.,Magowitz,J.,Ogilvie,GK.: :
Plasma and skin concentrations of polyunsaturated fatty acids before and after supplementation with n-3 fatty acids in dogs with atopic dermatitis. Am J Vet Res 66:868-73, 2005.
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2005 Steffan,J.,Parks,C.,Seewald,W.: :
Clinical trial evaluating the efficacy and safety of cyclosporine in dogs with atopic dermatitis. J Am Vet Med Assoc 226:1855-63, 2005.
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2004 Marsella,R.,Nicklin,CF.,Saglio,S.,Lopez,J.: :
Investigation on the clinical efficacy and safety of 0.1% tacrolimus ointment (Protopic) in canine atopic dermatitis: a randomized, double-blinded, placebo-controlled, cross-over study. Vet Dermatol 15:294-303, 2004.
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2004 Mueller,R.S.,Chapman,P.L.: :
Cross reactivity of airborne allergens based on 1000 intradermal test results. Aust Vet J 82:351-4, 2004.
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2004 Mueller,R.S.,Fieseler,K.V.,Fettman,M.J.,Zabel,S.,Rosychuk,R.A.,Ogilvie,G.K.,Greenwalt,T.L.: :
Effect of omega-3 fatty acids on canine atopic dermatitis. J Small Anim Pract 45:293-7, 2004.
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2004 Shaw,SC.,Wood,JL.,Freeman,J.,Littlewood,JD.,Hannant,D.: :
Estimation of heritability of atopic dermatitis in Labrador and Golden Retrievers. Am J Vet Res 65:1014-20, 2004.
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2004 Shida,M.,Kadoya,M.,Park,SJ.,Nishifuji,K.,Momoi,Y.,Iwasaki,T.: :
Allergen-specific immunotherapy induces Th1 shift in dogs with atopic dermatitis. Vet Immunol Immunopathol 102:19-31, 2004.
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2003 Arlian,L.G.,Schumann,R.J.,Morgan,M.S.,Glass,R.L.: :
Serum immunoglobulin E against storage mite allergens in dogs with atopic dermatitis American Journal of Veterinary Research 64:32-36, 2003.
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2003 Graham,L.F.,Torres,S.M.,Jessen,C.R.,Horne,K.L.,Hendrix,P.K.: :
Effects of propofol-induced sedation on intradermal test reactions in dogs with atopic dermatitis Veterinary Dermatology 14:167-76, 2003.
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2003 Olivry,T.,Mueller,R.S.,TheInternationalTaskForceonCanineAtopicDerm: :
Evidence-based veterinary dermatology: a systematic review of the pharmacotherapy of canine atopic dermatitis.[comment] Veterinary Dermatology 14:121-46, 2003.
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2002 Egli,K.S.,Schiessl,B.,Roosje,P.J.,Seewald,W.L.,Forster,U.,Peel,J.E.,Welle,M.M.: :
Evaluation of the usefulness of sensitization to aeroallergens as a model for canine atopic dermatitis in genetically predisposed Beagles American Journal of Veterinary Research 63:1329-1336, 2002.
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2002 Hillier,A.: :
Allergy testing and treatment for canine atopic dermatitis Veterinary Medicine 97:210-+, 2002.
2002 Hillier,A.: :
Definitively diagnosing atopic dermatitis in dogs Veterinary Medicine 97:198-+, 2002.
2002 Hillier,A.: :
Symposium on atopic dermatitis Veterinary Medicine 97:196, 2002.
2002 Jackson,H.A.,Orton,S.M.,Hammerberg,B.: :
IgE is present on peripheral blood monocytes and B cells in normal dogs and dogs with atopic dermatitis but there is no correlation with serum IgE concentrations Veterinary Immunology & Immunopathology 85:225-232, 2002.
2002 Jouppi,R.: :
Response to the letters regarding the treatment of canine atopic dermatitis with a homeopathic remedy Canadian Veterinary Journal - Revue Veterinaire Canadienne 43:910-911, 2002.
2002 Maeda,S.,Fujiwara,S.,Omori,K.,Kawano,K.,Kurata,K.,Masuda,K.,Ohno,K.,Tsujimoto,H.: :
Lesional expression of thymus and activation-regulated chemokine in canine atopic dermatitis Veterinary Immunology & Immunopathology 88:79-87, 2002.
2002 Mueller,R.S.,Chapman,P.L.,Rosychuk,R.E.W.,Bettenay,S.V.,Fieseler,K.V.: :
Evaluation of cross-reactivity of allergens by use of intradermal testing in atopic dogs American Journal of Veterinary Research 63:874-879, 2002.
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2002 Nuttall,T.J.,Knight,P.A.,McAleese,S.M.,Lamb,J.R.,Hill,P.B.: :
T-helper 1, T-helper 2 and immunosuppressive cytokines in canine atopic dermatitis Veterinary Immunology & Immunopathology 87:379-384, 2002.
2002 Nuttall,T.J.,Knight,P.A.,McAleese,S.M.,Lamb,J.R.,Hill,P.B.: :
Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis Clinical & Experimental Allergy 32:789-795, 2002.
2002 Nuttall,T.J.,Pemberton,A.D.,Lamb,J.R.,Hill,P.B.: :
Peripheral blood mononuclear cell responses to major and minor Dermatophagoides allergens in canine atopic dermatitis Veterinary Immunology & Immunopathology 84:143-150, 2002.
2002 Olivry,T.,Rivierre,C.,Jackson,H.A.,Murphy,K.M.,Davidson,G.,Sousa,C.A.: :
Cyclosporine decreases skin lesions and pruritus in dogs with atopic dermatitis: a blinded randomized prednisolone-controlled trial Veterinary Dermatology 13:77-87, 2002.
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2002 Scott,D.W.,Miller,W.H.,Senter,D.A.,Cook,C.P.,Kirker,J.E.,Cobb,S.M.: :
Treatment of canine atopic dermatitis with a commercial homeopathic remedy: A single-blinded, placebo-controlled study Canadian Veterinary Journal - Revue Veterinaire Canadienne 43:601-603, 2002.
2002 Sinke,J.D.,Rutten,V.P.M.G.,Willemse,T.: :
Immune dysregulation in atopic dermatitis Veterinary Immunology & Immunopathology 87:351-356, 2002.
2002 Yamashita,K.,Fujiwara,C.,Azuma,R.,Sawazaki,T.,Nakao,Y.,Hasegawa,A.: :
Determination of antigenic proteins of Housedust mites in 90 dogs suffering from atopic dermatitis Journal of Veterinary Medical Science 64:673-676, 2002.
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2002 Zur,G.,Ihrke,P.J.,White,S.D.,Kass,P.H.: :
Canine atopic dermatitis: a retrospective study of 266 cases examined at the University of California, Davis, 1992-1998. Part I. Clinical features and allergy testing results Veterinary Dermatology 13:89-102, 2002.
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2002 Zur,G.,White,S.D.,Ihrke,P.J.,Kass,P.H.,Toebe,N.: :
Canine atopic dermatitis: a retrospective study of 169 cases examined at the University of California, Davis, 1992-1998. Part II. Response to hyposensitization Veterinary Dermatology 13:103-111, 2002.
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2001 DeBoer,D.J.,Griffin,C.E.: :
The ACVD task force on canine atopic dermatitis (XXI): antihistamine pharmacotherapy. Vet Immunol Immunopathol 81:323-9, 2001.
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2001 DeBoer,D.J.,Hillier,A.: :
The ACVD task force on canine atopic dermatitis (XVI): laboratory evaluation of dogs with atopic dermatitis with serum-based "allergy" tests. Vet Immunol Immunopathol 81:277-87, 2001.
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2001 DeBoer,D.J.,Hillier,A.: :
The ACVD task force on canine atopic dermatitis (XV): fundamental concepts in clinical diagnosis. Vet Immunol Immunopathol 81:271-6, 2001.
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2001 DeBoer,D.J.,Marsella,R.: :
The ACVD task force on canine atopic dermatitis (XII): the relationship of cutaneous infections to the pathogenesis and clinical course of canine atopic dermatitis. Vet Immunol Immunopathol 81:239-49, 2001.
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2001 Griffin,C.E.,DeBoer,D.J.: :
The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis. Vet Immunol Immunopathol 81:255-69, 2001.
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2001 Griffin,C.E.,Hillier,A.: :
The ACVD task force on canine atopic dermatitis (XXIV): allergen-specific immunotherapy. Vet Immunol Immunopathol 81:363-83, 2001.
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2001 Halliwell,R.E.,DeBoer,D.J.: :
The ACVD task force on canine atopic dermatitis (III): the role of antibodies in canine atopic dermatitis. Vet Immunol Immunopathol 81:159-67, 2001.
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2001 Hill,P.B.,DeBoer,D.J.: :
The ACVD task force on canine atopic dermatitis (IV): environmental allergens. Vet Immunol Immunopathol 81:169-86, 2001.
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2001 Hill,P.B.,Hillier,A.,Olivry,T.: :
The ACVD task force on canine atopic dermatitis (VI): IgE-induced immediate and late-phase reactions, two inflammatory sequences at sites of intradermal allergen injections. Vet Immunol Immunopathol 81:199-204, 2001.
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2001 Hill,P.B.,Olivry,T.: :
The ACVD task force on canine atopic dermatitis (V): biology and role of inflammatory cells in cutaneous allergic reactions. Vet Immunol Immunopathol 81:187-98, 2001.
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2001 Hillier,A.,DeBoer,D.J.: :
The ACVD task force on canine atopic dermatitis (XVII): intradermal testing. Vet Immunol Immunopathol 81:289-304, 2001.
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2001 Hillier,A.,Griffin,C.E.: :
The ACVD task force on canine atopic dermatitis (I): incidence and prevalence. Vet Immunol Immunopathol 81:147-51, 2001.
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2001 Hillier,A.,Griffin,C.E.: :
The ACVD task force on canine atopic dermatitis (X): is there a relationship between canine atopic dermatitis and cutaneous adverse food reactions? Vet Immunol Immunopathol 81:227-31, 2001.
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2001 Marsella,R.,Olivry,T.: :
The ACVD task force on canine atopic dermatitis (VII): mediators of cutaneous inflammation. Vet Immunol Immunopathol 81:205-13, 2001.
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2001 Marsella,R.,Olivry,T.: :
The ACVD task force on canine atopic dermatitis (XXII): nonsteroidal anti-inflammatory pharmacotherapy. Vet Immunol Immunopathol 81:331-45, 2001.
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2001 Marsella,R.,Sousa,C.A.: :
The ACVD task force on canine atopic dermatitis (XIII): threshold phenomenon and summation of effects. Vet Immunol Immunopathol 81:251-4, 2001.
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2001 Mueller,R.S.,Bettenay,S.V.: :
Evaluation of the safety of an abbreviated course of injections of allergen extracts (rush immunotherapy) for the treatment of dogs with atopic dermatitis. Am J Vet Res 62:307-10, 2001.
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2001 Nuttall,T.J.,Halliwell,R.E.W.: :
Serum antibodies to Malassezia yeasts in canine atopic dermatitis Veterinary Dermatology 12:327-332, 2001.
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2001 Nuttall,T.J.,Lamb,J.R.,Hill,P.B.: :
Characterisation of major and minor Dermatophagoides allergens in canine atopic dermatitis Research in Veterinary Science 71:51-57, 2001.
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2001 Nuttall,T.J.,Lamb,J.R.,Hill,P.B.: :
Peripheral blood mononuclear cell responses to Dermatophagogoides farinae in canine atopic dermatitis Veterinary Immunology & Immunopathology 82:273-280, 2001.
2001 Olivry,T.,DeBoer,D.J.,Griffin,C.E.,Halliwell,R.E.,Hill,P.B.,Hillier,A.,Marsella,R.,Sousa,C.A.: :
The ACVD task force on canine atopic dermatitis: forewords and lexicon. Vet Immunol Immunopathol 81:143-6, 2001.
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2001 Olivry,T.,Hill,P.B.: :
The ACVD task force on canine atopic dermatitis (VIII): is the epidermal lipid barrier defective? Vet Immunol Immunopathol 81:215-8, 2001.
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2001 Olivry,T.,Hill,P.B.: :
The ACVD task force on canine atopic dermatitis (XVIII): histopathology of skin lesions. Vet Immunol Immunopathol 81:305-9, 2001.
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2001 Olivry,T.,Hill,P.B.: :
The ACVD task force on canine atopic dermatitis (IX): the controversy surrounding the route of allergen challenge in canine atopic dermatitis. Vet Immunol Immunopathol 81:219-25, 2001.
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2001 Olivry,T.,Marsella,R.,Hillier,A.: :
The ACVD task force on canine atopic dermatitis (XXIII): are essential fatty acids effective? Vet Immunol Immunopathol 81:347-62, 2001.
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2001 Olivry,T.,Sousa,C.A.: :
The ACVD task force on canine atopic dermatitis (XIX): general principles of therapy. Vet Immunol Immunopathol 81:311-6, 2001.
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2001 Olivry,T.,Sousa,C.A.: :
The ACVD task force on canine atopic dermatitis (XX): glucocorticoid pharmacotherapy. Vet Immunol Immunopathol 81:317-22, 2001.
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2001 Rees,C.A.: :
Canine and feline atopic dermatitis: A review of the diagnostic options Clinical Techniques in Small Animal Practice 16:230-232, 2001.
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2001 Sousa,C.A.,Halliwell,R.E.: :
The ACVD task force on canine atopic dermatitis (XI): the relationship between arthropod hypersensitivity and atopic dermatitis in the dog. Vet Immunol Immunopathol 81:233-7, 2001.
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2001 Sousa,C.A.,Marsella,R.: :
The ACVD task force on canine atopic dermatitis (II): genetic factors. Vet Immunol Immunopathol 81:153-7, 2001.
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2000 Masuda,K.,Tsujimoto,H.,Fujiwara,S.,Kurata,K.,Hasegawa,A.,Taniguchi,Y.,Yamashita,K.,Yasueda,H.,DeBoer,D.J.,de,Weck,A.L.,Sakaguchi,M.: :
IgE-reactivity to major Japanese cedar (Cryptomeria japonica) pollen allergens (Cry j 1 and Cry j 2) by ELISA in dogs with atopic dermatitis Veterinary Immunology & Immunopathology 74:263-270, 2000.
2000 McEwan,N.A.: :
Adherence by Staphylococcus intermedius to canine keratinocytes in atopic dermatitis Research in Veterinary Science 68:279-283, 2000.
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2000 Mueller,R.S.,Bettenay,S.V.,Tideman,L.: :
Aero-allergens in canine atopic dermatitis in southeastern Australia based on 1000 intradermal skin tests Australian Veterinary Journal 78:392-399, 2000.
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1999 DeBoer,D.J.,Hill,P.B.: :
Serum immunoglobulin E concentrations in West Highland White Terrier puppies do not predict development of atopic dermatitis Veterinary Dermatology 10:275-281, 1999.
1999 Mueller,R.S.,Burrows,A.,Tsohalis,J.: :
Comparison of intradermal testing and serum testing for allergen-specific IgE using monoclonal IgE antibodies in 84 atopic dogs Australian Veterinary Journal 77:290-294, 1999.
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1998 Hammerling,R.,Leidinger,K.: :
Canine atopic dermatitis - pathomechanisms and comparison of ict and elisa with monoclonal anti-ige-antibody [German] Praktische Tierarzt 79:509 ff., 1998.
1998 Prelaud,P.,Guaguere,E.,Alhaidari,Z.,Faivre,N.,Heripret,D.,Gayerie,A.: :
Reevaluation of diagnostic criteria of canine atopic dermatitis [French] Revue de Medecine Veterinaire 149:1057-1064, 1998.
1997 Mueller,R.S.,Cannon,A.,Reubl,G.H.,Ihrke,P.J.: :
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1997 Olivry,T.,Naydan,D.K.,Moore,P.F.: :
Characterization of the cutaneous inflammatory infiltrate in canine atopic dermatitis American Journal of Dermatopathology 19:477-486, 1997.
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Langerhans cell hyperplasia and ige expression in canine atopic dermatitis Archives of Dermatological Research 288:579-585, 1996.
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1974 Austin,V.H.: :
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