The detail information of Coat colour, agouti
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: no

Year key mutation first reported: 2004

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
There are associated breeds.
Associated Gene
Symbol Description Species Position Other Links
ASIP agouti signaling protein Canis lupus familiaris Chr24 : 24041356 - 24084629 Homologene, Ensembl, NCBI gene
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Dreger,D.L.,Anderson,H.,Donner,J.,Clark,J.A.,Dykstra,A.,Hughes,A.M.,Ekenstedt,K.J.: :
Atypical Genotypes for Canine <i>Agouti Signaling Protein</i> Suggest Novel Chromosomal Rearrangement. Genes (Basel) 11:, 2020.
Pubmed reference: 32635139 . DOI: 10.3390/genes11070739 .
2013 Ciampolini,R.,Cecchi,F.,Spaterna,A.,Bramante,A.,Bardet,S.M.,Oulmouden,A.: :
Characterization of different 5'-untranslated exons of the ASIP gene in black-and-tan Doberman Pinscher and brindle Boxer dogs. Anim Genet 44:114-7, 2013.
Pubmed reference: 22524303 . DOI: 10.1111/j.1365-2052.2012.02364.x .
2013 Dreger,D.L.,Parker,H.G.,Ostrander,E.A.,Schmutz,S.M.: :
Identification of a mutation that is associated with the saddle tan and black-and-tan phenotypes in Basset Hounds and Pembroke Welsh Corgis. J Hered 104:399-406, 2013.
Pubmed reference: 23519866 . DOI: 10.1093/jhered/est012 .
2012 Dreger,D.L.,Schmutz,S.M.: :
A case of canine chimerism diagnosed using coat color tests. Mol Cell Probes 26:253-5, 2012.
Pubmed reference: 22433982 . DOI: 10.1016/j.mcp.2012.03.004 .
2011 Dreger,D.L.,Schmutz,S.M.: :
A SINE Insertion Causes the Black-and-Tan and Saddle Tan Phenotypes in Domestic Dogs. J Hered :S11-8, 2011.
Pubmed reference: 21846741 . DOI: 10.1093/jhered/esr042 .
2011 Oguro-Okano,M.,Honda,M.,Yamazaki,K.,Okano,K.: :
Mutations in the melanocortin 1 receptor, β-defensin103 and agouti signaling protein genes, and their association with coat color phenotypes in Akita-inu dogs. J Vet Med Sci 73:853-8, 2011.
Pubmed reference: 21321476 .
2007 Schmutz,SM.,Berryere,TG.,Barta,JL.,Reddick,KD.,Schmutz,JK.: :
Agouti sequence polymorphisms in coyotes, wolves and dogs suggest hybridization. J Hered 98:351-5, 2007.
Pubmed reference: 17630272 . DOI: 10.1093/jhered/esm036 .
2005 Berryere,TG.,Kerns,JA.,Barsh,GS.,Schmutz,SM.: :
Association of an Agouti allele with fawn or sable coat color in domestic dogs. Mamm Genome 16:262-72, 2005.
Pubmed reference: 15965787 . DOI: 10.1007/s00335-004-2445-6 .
2004 Kerns,JA.,Newton,J.,Berryere,TG.,Rubin,EM.,Cheng,JF.,Schmutz,SM.,Barsh,GS.: :
Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs. Mamm Genome 15:798-808, 2004.
Pubmed reference: 15520882 . DOI: 10.1007/s00335-004-2377-1 .
2003 Kerns,JA.,Olivier,M.,Lust,G.,Barsh,GS.: :
Exclusion of melanocortin-1 receptor (mc1r) and agouti as candidates for dominant black in dogs. J Hered 94:75-9, 2003.
Pubmed reference: 12692166 .