The detail information of Progressive retinal atrophy, Basenji
OMIA Basic Information
Possible human homologues (MIM numbers):
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Recessive
Considered a defect: yes
Year key mutation first reported: 2013
Species-specific name: -
Species-specific symbol: -
More detail information can see in
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | History | Breed Source |
|---|---|---|---|---|---|---|
| CB20 | Basenji(African Barkless Dog) | 43.2 cm (male), 40.6 cm (female) | 10.9 kg (male), 10 kg (female) | Democratic Republic of the Congo |
Associated Gene
| Symbol | Description | Species | Position | Other Links |
|---|---|---|---|---|
| SAG | S-antigen; retina and pineal gland (arrestin) | Canis lupus familiaris | Chr25 : 45060350 - 45103430 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2013 |
Goldstein,O.,Jordan,J.A.,Aguirre,G.D.,Acland,G.M.: :
A non-stop S-antigen gene mutation is associated with late onset hereditary retinal degeneration in dogs. Mol Vis 19:1871-84, 2013. Pubmed reference: 24019744 . |
| 2006 |
Goldstein,O.,Zangerl,B.,Pearce-Kelling,S.,Sidjanin,D.J.,Kijas,J.W.,Felix,J.,Acland,G.M.,Aguirre,G.D.: :
Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome. Genomics 88:541-50, 2006. Pubmed reference: 16859891 . DOI: 10.1016/j.ygeno.2006.05.013 . |