The detail information of Spina bifida
Basic Information

Disease Description: A developmental abnormality where some vetebra are malformed thereby exposing the spinal cord.

Inherit Mode: The condition is thought to be inherited, but the mode of inheritance has not been identified.

Disease Symptom: Most often, spina bifida occurs in the lower back region (caudal lumbar spine). The clinical signs vary with the extent of the defect. With a mild defect, you will likely never know there is an abnormality unless your dog has x-rays that show the area. When the spinal cord itself is affected, you will see signs in the hind end ranging from weakness and incoordination to paralysis and urinary and fecal incontinence. With a severe defect (absence of several adjacent vertebral arches with protrusion of spinal cord), signs are generally evident very early, when pups start to walk.

Disease Cause: -

Disease Diagnose: In severe cases in young pups, your veterinarian may recognize the condition on physical examination. Diagnosis is confirmed by x-ray. With a mild defect, your veterinarian may find this abnormality incidentally when an x-ray is performed.

Treat Method: There is no effective treatment for dogs with spinal cord malformations. No treatment is necessary for dogs in whom spina bifida is discovered incidentally on radiographs. Reconstructive surgery may be helpful for mildly affected animals.

Breeder Advice: Although the mode of inheritance has not been established, it is safest not to breed from families where spina bifida has occurred.

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Spina bifida - - -
Spina bifida occulta - - - -
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB17 Australian Terrier Affectionate, Courageous, Spirited 25.4-27.9 cm 5.4-8.2 kg Australia
CB46 Boston Terrier Friendly, bright, amusing, and adaptable. 38.1-43.2 cm 4.5-11.3 kg United States
CB58 English Bulldog Calm, courageous, and friendly; dignified but amusing. 35.6-38.1 cm 22.7 kg (male), 18.1 kg (female) United Kingdom (England)
CB71 Chihuahua Graceful, charming, and sassy. 15.2-22.9 cm 1.4-2.7 kg Mexico
CB84 Dalmatian Stable, Outgoing;Dignified but never shy 48.3-61 cm 20.4-31.8 kg Croatia
CB196 Pug Even-tempered, charming, mischievous and loving 25.4-33 cm 6.4-8.2 kg China
CB210 Samoyed Gentle, adaptable, eager, friendly; conservative but never shy 53.3-59.7 cm (male), 48.3-53.3 cm (female) 20.4-29.5 kg (male), 15.9-22.7 kg (female) Russia
References
2021 Zarzycki,A.,Thomas,Z.M.,Mazrier,H.: :
Comparison of inherited neural tube defects in companion animals and livestock. Birth Defects Res 113:319-348, 2021.
Pubmed reference: 33615733 . DOI: 10.1002/bdr2.1848 .
1995 LeCouteur, R.A., Child, G. :
Diseases of the spinal cord W.B. Saunders Co., Toronto. S.J. Ettinger and E.C. Feldman (eds.) Textbook of Veterinary Internal Medicine, pp. 629-696
1992 Bailey,C.S.,Morgan,J.P.: :
Congenital spinal malformations. Vet Clin North Am Small Anim Pract 22:985-1015, 1992.
Pubmed reference: 1641930 .
1973 Parker,A.J.,Park,R.D.,Byerly,C.S.,Stowater,J.L.: :
Spina bifida with protrusion of spinal cord tissue in a dog Journal of the American Veterinary Medical Association 163:158-160, 1973.
Pubmed reference: 4577614 .