Another Name: Hypertrophic Osteodystrophy

Disease Description: Any of a number of diseases involving the development of the bones.

Inherit Mode: -

Disease Symptom: Symmetrical lameness (mild or severe), most often in the forelimbs, Depression and reluctance to move, Warm, swollen metaphyses (the soft, or growing part of the long bones in puppies), Fever, as high as 106° F, Lack of appetite, Weight loss, Dehydration, Diarrhea, Possible pneumonia

Disease Cause: Suspected (but not proven) to be a reaction in the bone-producing centers to vaccination.

Disease Diagnose: Your veterinarian will perform a thorough physical exam of your pet. While a chemical blood profile, a complete blood count, and a urinalysis are good indicators of possible systemic disease, radiograph imaging of the legs is crucial for diagnosis of hypertrophic osteodystrophy. Thoracic (chest) radiographs will also be taken if pneumonia is suspected.

Treat Method: There is no cure for this disease, but most puppies will recover on their own after one or two episodes. This disease can last from days to weeks, and puppies may be left with permanently bowed legs. Puppies that will not, or cannot stand or move should be hospitalized with bed rest, and turned frequently by the nursing staff. If the puppy is dehydrated, fluid therapy will also be administered. A feeding tube can be inserted if your puppy is unable to eat. Your veterinarian will probably prescribe anti-inflammatory medicine to treat your puppy’s pain symptoms.

Breeder Advice: You should only walk your puppy on a leash during episodes. All other physical activity, such as freely running and jumping, should be restricted. The puppy should be given a small, confined, well-padded area where it can rest when it is not being walked. Puppies can be fed their normal diet, but supplements, especially Vitamin C supplements, should be avoided. If your puppy shows any signs of systemic disease, such as bloody diarrhea, spitting up blood, pneumonia, weight loss, or any other change in its condition, you should call your veterinarian immediately for advisement.

Disease Description Source: Link