Disease Description: Any of a number of diseases affecting the bones due to an abnormality of metabolism.

Inherit Mode: -

Disease Symptom: Symptoms and signs depend upon the type of enzyme deficiency, type of GAG stored, and the tissue in which storage occurs. Some of the more common ones include: Dwarfism, Severe bone disease, Degenerative joint disease (DJD), including partial dislocation of hip joint, Facial structural deformity, Enlarged liver, Enlarged tongue, Eye cloudiness

Disease Cause: In view of the age of the dog and the fact that humoral hypercalcemia of malignancy could be a possible underlying cause for the osteopenia, thoracic radiographs were taken to check for the presence of neo- plasia.

Disease Diagnose: The severe osteopenia was indicative of metabolic bone disease for which NSHP, rickets/osteomalacia, primary hyperparathyroidism, humoral hypercalcemia of malignancy, renal osteodystrophy and hypervitaminosis A are important differential diagnose

Treat Method: The treatment consisted mainly of dietary correction of the ration by providing a balanced commercial diet. Castration was recommended because of the benign prostate hyperplasia, and endoscopic evaluation of the gastrointestinal tract was advised if any further episodes of diarrhea should occur.

Breeder Advice: -

Disease Description Source: Link