The detail information of Factor II deficiency or hypoprothrombinemia
Basic Information

Another Name: hypoprothrombinemia

Disease Description: A rare deficiency of prothrombin, a clotting factor needed to control bleeding.

Inherit Mode: -

Disease Symptom: Clinical symptoms are primarily mild to moderately severe bleeding, epistaxis and umbilical bleeding in newborn puppies.In adult dogs, subpepidermal hematomas and dermatitis may also occur but episodes of bleeding tend to become less frequent.

Disease Cause: -

Disease Diagnose: -

Treat Method: No treatment is usually required, although in severely affected pups, intravenous frozen plasma or cryoprecipitate may be required.

Breeder Advice: -

Disease Description Source: Link

Associated Diseases
There are no associated diseases in OMIA/CIDD.
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB49 Boykin Spaniel Friendly, eager, trainable, lovable 39.4-45.7 cm (male), 35.6-41.9 cm (female) 13.6-18.1 kg (male), 11.3-15.9 kg (female) United States
CB95 English Foxhound Affectionate, Gentle, Sociable 61 cm 27.2-34 kg United Kingdom (England)
CB107 French Spaniel Friendly, outgoing personality, well balanced and patient,eager to please, can be trained easily France
CB176 Papillon(Continental Toy Spaniel) Happy, alert, friendly 20.3-27.9 cm 2.3-4.5 kg Spain, Belgium, France
References
1986 Bonk RJ et al :
Automated synthetic substrate assays for coagulopathies of dogs Lab Anim Sci '36(5):517-21
Pubmed reference: _ . DOI: _ .
1982 Hill BL et al :
Prothrombin deficiency in a cocker spaniel J Am Vet Med Assoc 181(3):262-263
Pubmed reference: _ . DOI: _ .
1940 Fouts, PJ et al :
Factor II deficiency in dogs J Nutrition
Pubmed reference: _ . DOI: _ .