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Mumps virus - NA

Virus Host Enzyme Edited Genes Phenotype Disease Details
Mumps virus Human NA Phosphoprotein (P) gene Produce new protein Nonpurulent swelling of the parotid gland
  • Edited Gene Alias: P gene
  • Editing Site: NA
  • Editing Type: G insertion
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: Positive
  • Description: An unedited mRNA was shown to encode the mumps virus cysteine-rich protein V, and mRNA transcripts containing two and four inserted G residues were translated to yield the mumps virus P and I proteins, respectively.
  • PMID: 2166809
Mumps virus Human NA Phosphoprotein (P) gene Produce new protein Nonpurulent swelling of the parotid gland
  • Edited Gene Alias: P gene
  • Editing Site: NA
  • Editing Type: G insertion
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: Negative
  • Description: Nucleotide sequence evidence that suggests that the generation of these proteins in mumps virus is similar to the process demonstrated for SV5. This provides an explanation for the generation of the non- structural proteins of mumps virus.
  • PMID: 2165137
Mumps virus Human NA Phosphoprotein (P) gene Affact virus pathogenicity Nonpurulent swelling of the parotid gland
  • Edited Gene Alias: P gene
  • Editing Site: NA
  • Editing Type: G insertion
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: Negative
  • Description: There has been evidence that RNA editing may vary between strains of measles virus(MV). Differences in editing frequencies could result in variation in the relative amounts of the P and V proteins. Because P is a required co-factor for replication and V acts as an inhibitor of innate immune responses, changes in the levels of expression of these two proteins could affect the pathogenicity of the virus.
  • PMID: 18490071