Woodchuck hepatitis virus - WHD

Virus Host Enzyme Edited Genes Phenotype Disease Details
Woodchuck hepatitis virus Woodchuck ADAR1 NA RNA editing occurred within an eight-nucleoti Hepatitis
  • Edited Gene Alias: NA
  • Editing Site: 1012
  • Editing Type: NA
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: NA
  • Description: From the sequences of 31 clones, we found 32% (10 of 31) to be identical to the original single nucleotide sequence. For the remainder, there were neither insertions nor deletions but there was a small number of single-nucleotide changes. These changes were predominantly transitions rather than transversions. Furthermore, the transitions were largely of just two types, uridine to cytidine and adenosine to guanosine. Of the 40 changes detected on HDV, 35% (14 of 40) occurred within an eight-nucleotide region that included position 1012, previously shown to be a site of RNA editing.
  • PMID: 7853505