URL: | http://tagc.univ-mrs.fr/tbrowser |
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Description: | TranscriptomeBrowser host a large database of transcriptional signatures (TS, n~40 000) extracted from Gene Expression Omnibus (~4 000 experiments) using the DBF-MCL algorithm. TBrowser comes with a sophisticated search engine so that users can search for the biological contexts in which several genes were concomitantly regulated. InteractomeBrowser is a default plug-in of TranscriptomeBrowser software (a video tutorial is available here). InteractomeBrowser is intented to display interactions networks, given an input list of genes (user-defined or stored in the TranscriptomeBrowser database). |
Year founded: | 2008 |
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Version: | 3.0 |
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Country/Region: | France |
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University/Institution: | Parc Scientifique de Luminy |
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Country/Region: | France |
Contact name (PI/Team): | Denis Puthier |
Contact email (PI/Helpdesk): | puthier@tagc.univ-mrs.fr |
TranscriptomeBrowser 3.0: introducing a new compendium of molecular interactions and a new visualization tool for the study of gene regulatory networks. [PMID: 22292669]
BACKGROUND: Deciphering gene regulatory networks by in silico approaches is a crucial step in the study of the molecular perturbations that occur in diseases. The development of regulatory maps is a tedious process requiring the comprehensive integration of various evidences scattered over biological databases. Thus, the research community would greatly benefit from having a unified database storing known and predicted molecular interactions. Furthermore, given the intrinsic complexity of the data, the development of new tools offering integrated and meaningful visualizations of molecular interactions is necessary to help users drawing new hypotheses without being overwhelmed by the density of the subsequent graph. |
TranscriptomeBrowser: a powerful and flexible toolbox to explore productively the transcriptional landscape of the Gene Expression Omnibus database. [PMID: 19104654]
BACKGROUND: As public microarray repositories are constantly growing, we are facing the challenge of designing strategies to provide productive access to the available data. |