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Jian Sang
Jian Sang

PhD Candidate

Gene Expression Nebulas

Email: sangj (AT) big.ac.cn

Tel: +86 (10) 8409-7845

PROFESSIONAL EXPERIENCE

  • Intern Researcher, Beijing Institute of Genomics, Chinese Academy of Sciences (CAS), China, 2015.04−2016.08

VISITING EXPERIENCE

  • Visiting Student, Friedrich-Schiller-Universität Jena, Deutschland, 2014.10-2015.03

EDUCATION

  • PhD in Bioinformatics, Beijing Instiute of Genomics, Chinese Academy of Sciences, China, 2016.09 - Now

  • MS in Biochemistry & Molecular Biology, Chinese Academy of Forestry, China, 2011.09 - 2014.07

  • BS in Plant Science & Technology, Huazhong Agricultural University (HZAU), China, 2007.09-2011.07

RESEARCH INTERESTS

  • Omics integration and deep mining

  • Transcriptome and epigenome bioinformatics

PROJECTS & RESOURCES

  1. The ICG Project (http://icg.big.ac.cn/)

  2. The IC4R Project (http://ic4r.org)

  3. Genome Warehouse (http://bigd.big.ac.cn/gwh/)

  4. EWAS Atlas (http://bigd.big.ac.cn/ewas/)

  5. Editome Disease Knowledgebase (http://bigd.big.ac.cn/edk/)

  6. Plant Editosome Database (http://bigd.big.ac.cn/ped/home) 

  7. Rice genome reannotation based on large-scale integration of RNA-Seq data

  8. Exploration of the response mechanism underlying Heavy-Metal stress in Sedum, by miRNAs and mRNA sequencing

  9. Co-expression network analysis of rice transcriptome exposed to Pi-Starvation stress

HONORS & AWARDS

  • 2019-06           The “2019 Outstanding Graduates” in the University of Chinese Academy of Sciences

  • 2019-06           The “2019 Outstanding Graduates” in Beijing

  • 2018-11           The “2018 National Scholarship for Doctoral student”

  • 2018-09           The “UCAS-BHPB Excellent Student” Award

  • 2018-06           The “Triple-A student” in the University of Chinese Academy of Science

  • 2017-11           The “Outstanding representative student” in Beijing Institute of Genomics

  • 2014-07           The “2014 Outstanding graduates” in Beijing

  • 2014-06           The “2014 Outstanding graduates” in Chinese Academy of Forestry

  • 2013-12           The 2013 National scholarship for Master student

PUBLICATIONS

(1) Multi-Omics integration and knowledge mining

  1. Sang J# as co-first author in BIG Data Center Members: Database Resources of the BIG Data Center in 2019. Nucleic Acids Research 2019, in press. [PMID=30365034]

  2. Sang J#, Wang Z#, Li M, Cao J, Niu G, Xia L, Zou D, Wang F, Xu X, Han X, Fan J, Yang Y, Zuo W, Zhang Y, Zhao W, Bao Y, Xiao J, Hu S, Hao L, Zhang Z*: ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization. Nucleic Acids Research 2018, 46(D1):D121-D126. [PMID=29036693] 

  3. Sang J# as co-first author in BIG Data Center Members: Database Resources of the BIG Data Center in 2018. Nucleic Acids Research 2018, 46(D1):D14-D20. [PMID=29036542]

  4. Sang J# as co-first author in BIG Data Center Members: The BIG Data Center: from deposition to integration to translation. Nucleic Acids Research 2017, 45(D1):D18-D24. [PMID=27899658]

  5. Sang J as co-author in the IC4R Project Consortium: Information Commons for Rice (IC4R). Nucleic Acids Research 2016, 44(D1):D1172-1180. [PMID=26519466]

  6. Zhang Z*, Sang J, Ma L, Wu G, Wu H, Huang D, Zou D, Liu S, Li A, Hao L, Tian M, Xu C, Wang X, Wu J, Xiao J, Dai L, Chen LL, Hu S, Yu J: RiceWiki: a wiki-based database for community curation of rice genes. Nucleic Acids Research 2014, 42:D1222-1228. [PMID=24136999]

  7. Dai L#, Xu C#, Tian M#, Sang J#, Zou D, Li A, Liu G, Chen F, Wu J, Xiao J, Wang X, Yu J, Zhang Z*: Community intelligence in knowledge curation: an application to managing scientific nomenclature. PLoS One 2013, 8(2):e56961. [PMID=23451119]

(2) Transcriptomic analysis and application 

  1. Sang J#, Zou D#, Wang ZN#, Wang F, Zhang YS, Xia L, Li ZH, Ma LN, Li MW, Xu BX, Liu XN, Wu SY, Liu L, Niu GY, Li M, Luo YF, Hu SN, Hao LL, Zhang Z*: Rice Genome Reannotation Using Massive RNA-Seq Data in IC4R. Genomics Proteomics & Bioinformatics 2019, in press.

  2. Sang J#, Han X#, Liu M, Qiao, G, Jiang J, Zhuo R*: Selection and Validation of Reference Genes for Real-Time Quantitative PCR in Hyperaccumulating Ecotype of Sedum alfrediiunder Different Heavy Metals Stresses. PLoS One 2013, 8 (12):e82927. [PMID=24340067]

  3. Xia L, Zou D, Sang J, Xu XJ, Yin HY, Li MW, Wu SY, Hu SN, Hao LL, Zhang Z*: Rice Expression Database (RED): an integrated RNA-Seq-derived gene expression database for rice. Journal of Genetics and Genomics 2017, 44(5):235-241. [PMID=28529082]

  4. Zhang Y, Han X, Sang J, He X, Liu M, Qiao G, Zhuo R*, He G, Hu J. Transcriptome analysis of immature xylem in the Chinese firat different developmental phases. PeerJ 2016, doi: 10.7717/peerj.2097. [PMID=27330860]

  5. Han X, Yin H, Song X, Zhang Y, Liu M, Sang J, Jiang J, Li J, Zhuo R*. Integration of small RNAs, degradome and transcriptome sequencing in hyperaccumulator Sedum alfrediiuncovers a complex regulatory network and provides insights into cadmium phytoremediation. Plant Biotechnology Journal 2016, doi: 10.1111/pbi.12512. [PMID=26801211]

  6. Liu M, Qiao G, Jiang J, Han X, Sang J, Zhuo R*. Identification and expression analysis of salt-responsive genes using a comparative microarray approach in Salix matsudana. Molecular biology reports 2014, 41(10), 6555-6568. [PMID=24993115]

(3) Epigenomics integration and analysis 

  1. Li M, Zou D, Li Z, Gao R, Sang J, Zhang Y, Li R, Xia L, Zhang T, Niu G, Bao Y, Zhang Z*: EWAS Atlas: a curated knowledgebase of epigenome-wide association studies. Nucleic Acids Research 2019, in press. [PMID=30364969]

  2. Niu G, Zou D, Li M, Zhang Y, Sang J, Xia L, Li M, Liu L, Cao J, Zhang Y, Wang P, Hu S, Hao L, Zhang Z*: Editome Disease Knowledgebase (EDK): A curated knowledgebase of editome-disease associations in human. Nucleic Acids Research 2019, in press. [PMID=30357418]

  3. Li M, Xia L, Zhang Y, Niu G, Li M, Wang P, Zhang Y, Sang J, Zou D, Hu S, Hao L, Zhang Z*: Plant Editosome Database: a curated database of RNA editosome in plants. Nucleic Acids Research 2019, in press. [PMID=30364952]

(4) Functional genetic exploration

  1. Chen S, Han X, Fang J, Lu Z, Qiu W, Liu M, Sang J, Jiang J, Zhuo R. Zhuo R*. Sedum alfredii SaNramp6 Metal Transporter Contributes to Cadmium Accumulation in Transgenic Arabidopsis thaliana. Scientific Reports 2017, 17;7(1):13318. [PMID=29042608]

  2. Liu M, Qiu W, He X, Zheng L, Song X, Han X, Jiang J, Qiao G, Sang J, Liu M, Zhuo R*. Functional Characterization of a Gene in Sedum alfredii Hance Resembling Rubber Elongation Factor Endowed with Functions Associated with Cadmium Tolerance. Frontiers in Plant Science 2016. [PMID=27446189]