Online Tools - Resource for Coronavirus 2019

Variation Annotation

This tool can perform functional annotation on the mutation site, display the change of the gene, code and amino acid in the mutation site, and the degree of influence on the gene function. In the current version, only NC_045512 is supported as reference for the online annotation. Both formats of bed and vcf files are supported.

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Bed format

Vcf format

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#Reference	Start position	End position	Base
NC_045512	1	1	T
NC_045512	10	10	C
NC_045512	1	2	TT
NC_045512	1	2	A
NC_045512	490	490	C

*Input file(s) should be separated by ‘tab’. The first column is the Chromosome of the reference genome - NC_045512; the second and third column is the start position and end position of the reference genome, respectively; the fourth column is the base mutation of the virus strain studied by users at the location.

#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT
NC_045512	1	cov1	A	T	.	.	.	GT
NC_045512	2	cov2	TA	T	.	.	.	GT
NC_045512	3	cov3	AA	T	.	.	.	GT
NC_045512	4	cov4	AG	A	.	.	.	GT
NC_045512	5	cov5	GG	A	.	.	.	GT

*Input file(s) should be separated by ‘tab’. The first column is the Chromosome of the reference genome - NC_045512; the second is the position of the reference genome; the third column is ID; the four column is reference allele; respectively, the fifth column is the base mutation of the virus strain studied by users at the location.