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China National Center for Bioinformation
Haplotype maps of novel coronavirus across the whole world and China are constructed, respectively, based on the genome variation information obtained from available high-quality genome sequences.
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Phylogeny tree of novel coronavirus across the whole world are constructed using BEAST, based on the genome variation information obtained from available high-quality genome sequences.
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Combining the mutation information of S gene and the structure information of S protein to annotated the position of the mutation site causing amino acid change in the protein structure.
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This work was developed and maintained by China National Center for Bioinformation (CNCB) / National Genomics Data Center (NGDC), and supported by the 13th Five-year Informatization Plan of Chinese Academy of Sciences (No. XXH13505-05), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA19090116，XDA08020102), the Genomics Data Center Construction of Chinese Academy of Sciences (0202), the Youth Innovation Promotion Association of Chinese Academy of Sciences and CAS Key Technology Talent Program.
China National Center for Bioinformation (CNCB) / Beijing Institute of Genomics, Chinese Academy of Sciences
(BIG)
National Gemomics Data Center (NGDC)
Email: GWH@big.ac.cn
Telephone: +86 (10) 8409-7340
Fax: +86 (10) 8409-7200
Address: No.1 Beichen West Road, Chaoyang District, Beijing 100101, China
The genome sequences of 3 novel coronavirus strains, Wuhan-Hu-1, WHU01 and WHU02 are re-assembled using raw sequencing data. Sequence comparison and colinearity analyses show that the newly assembled sequences are nearly identical to the released genome sequences, indicating the accuracy of the genome sequences. In addition, compared with strain Wuhan-Hu-1, WHU01 and WHU02 lack short sequences at both ends of the genome, mainly due to the different repeat number of nucleotide ‘A’ in terminal noncoding regions.
NGDC