Basic information
Locus name	AT4G37000
Alias	ACD2/RCCR
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Chlorophyll degradation
Effect for Senescence	delay
Gene Description	ACCELERATED CELL DEATH 2. High level of ACD2 Protein Abundance in Senescence and Pathogen Attack. ACD2/RCCR should function during the breakdown of chlorophyll in senescence and pathogen attack.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Greenberg JT, Guo A, Klessig DF, Ausubel FM Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions. Cell 1994 May 20;77(4):551-63 2: Mach JM, Castillo AR, Hoogstraten R, Greenberg JT The Arabidopsis-accelerated cell death gene ACD2 encodes red chlorophyll catabolite reductase and suppresses the spread of disease symptoms. Proc. Natl. Acad. Sci. U.S.A. 2001 Jan 16;98(2):771-6 3: Yao N, Greenberg JT Arabidopsis ACCELERATED CELL DEATH2 modulates programmed cell death. Plant Cell 2006 Feb;18(2):397-411
Pathway	KEGG map00860 (EC 1.3.1.80) MetaCyc PWY-5098
Sequence	AT4G37000.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name acd2 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type EMS
Mutated 2 Mutant name 35S-RCCR-GFP Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Ortholog Group
Ortholog Groups: OG5_178000	Accession Taxon NP_195417 ( AT4G37000 ) Arabidopsis thaliana NP_001064500 Oryza sativa Japonica Group e_gw1.83.94.1 Physcomitrella patens subsp. patens 30115.m001197 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description Pfam PF06405 6.9E-119 61 316 IPR009439 Red chlorophyll catabolite reductase Coils Coil NA 259 280 No hit NA
Subcellular Localization
Localization 1 Localization chloroplast Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization plastid Evidence SUBAcon Pubmed ID 23180787