| ENSCAFG00000000807 |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0000978 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0000980 |
RNA polymerase II distal enhancer sequence-specific DNA binding |
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0000981 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0001085 |
RNA polymerase II transcription factor binding |
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0001102 |
RNA polymerase II activating transcription factor binding |
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0001191 |
transcriptional repressor activity, RNA polymerase II transcription factor binding |
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0003705 |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding |
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II. |
IEA |
molecular_function |
| ENSCAFG00000000807 |
GO:0043565 |
sequence-specific DNA binding |
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
IEA |
molecular_function |