Disease Description: Gastric dilatation-volvulus (GDV) is a very serious condition that occurs in susceptible dogs when the stomach becomes distended with air, and then while dilated, twists on itself.
Inherit Mode: It appears that conformation and size are what predispose a particular breed to this disorder, such that breeds with a deeper and narrower chest are most susceptible. Within such a breed, dogs with a higher thoracic depth/width ratio (ie. the deepest, narrowest chests) are the most vulnerable to GDV.
Disease Symptom: GDV is one of those thankfully rare conditions in which your dog can go from being healthy to critically ill over the course of a few hours. Even with appropriate veterinary care, approximately one third of dogs with this condition will die. Initiation of GDV occurs when a susceptible dog swallows air while gulping food or water, possibly in association with exercise. You will first notice that your dog is uncomfortable - pacing, restless - and appears bloated. There may be unproductive retching/vomiting. Discomfort progresses to depression and if the dog does not receive treatment, to coma and death. This can all happen within 6 hours or less.
Disease Cause: -
Disease Diagnose: GDV must be diagnosed and treatment initiated quickly if your dog is to survive. The condition is usually readily diagnosed on physical examination.
Treat Method: The two urgent priorities are to remove the gas from the stomach (via stomach tube) and start treatment for shock. Your veterinarian will then perform surgery to reposition the stomach, assess the extent of damage, and do a gastropexy to anchor the stomach to the abdominal wall and prevent recurrence of GDV. Intensive care is required in the immediate post-operative period when dogs may face a number of life-threatening problems including shock, electrolyte imbalance, cardiac arrhythmias, and wide-spread infection (septicemia). Prevention:There are some simple things you can do to reduce the chance of bloat, if you have a dog of a susceptible breed. Basically, you want to avoid your dog consuming a large amount of food or water all at once, especially not at the same time as vigorous exercise. Rather than feeding once a day or leaving food always available, feed in divided portions. Have fresh clean water always accessible but take it up at mealtimes (so your dog doesn't gulp it with food). Avoid exercising your dog before and after meal times.
Breeder Advice: It may be possible to reduce the incidence of GDV in susceptible breeds by selectively breeding dogs with lower thoracic depth/width ratios.
Disease Description Source: Link
Disease Name | Other Name | Mode of inheritance | Link ID | Possible OMIM ID | Gene |
---|---|---|---|---|---|
Gastric dilatation volvulus syndrome | - | Multifactorial | - |
iDog Breed Number | Breed Name | Personality | Height | Weight | Breed Source |
---|---|---|---|---|---|
CB39 | Bloodhound | Sweet, easygoing, friendly to all; intense when working | 63.5-68.6 cm (male), 58.4-63.5 cm (female) | 40.8-49.9 kg (male), 36.3-45.4 kg (female) | Belgium, France |
CB45 | Borzoi(Russian wolfhound) | Loyal, affectionate, regally dignified; a charming but independent-minded canine nobleman | 71.1 cm & up (male), 66 cm & up (female) | 34-47.6 kg (male), 27.2-38.6 kg (female) | Russia |
CB47 | Bouvier des Flandres(Flanders Cattle Dog) | Strong-willed, even-tempered, courageous; affectionate with family, intimidating to intruders | 62.2-69.9 cm (male), 59.7-67.3 cm (female) | 31.8-49.9 kg | Belgium |
CB48 | German Boxer | Fun-loving, bright, active and loyal | 58.4-63.5 cm (male), 54.6-59.7 cm (female) | 29.5-36.3 kg (male), females are about 6.8 kg less than male | Germany |
CB53 | Berger Briard | Smart, Confident, Faithful | 58.4-68.6 cm (male), 55.9-64.8 cm (female) | 24.9-45.4 kg | France |
CB110 | German Shepherd Dog | Smart, confident, courageous, and steady; a true dog lover's dog | 61-66 cm (male), 55.9-61 cm (female) | 29.5-40.8 kg (male), 22.7-31.8 kg (female) | Germany |
CB117 | Gordon Setter | Bold, confident, and resolute afield; sweetly affectionate by the fireside | 61-68.6 cm (male), 58.4-66 cm (female) | 24.9-36.3 kg (male), 20.4-31.8 kg (female) | United Kingdom (Scotland) |
CB119 | Great Dane | Friendly, patient, & dependable. | 76.2-86.4 cm (male), 71.1-81.3 cm (female) | 54.4-90.7 kg (male), 44.9-59 kg (female) | Germany |
CB131 | Irish Setter | Outgoing, sweet-natured, active, and trainable | 68.6 cm (male), 63.5 cm (female) | 31.8 kg (male), 27.2 kg (female) | Ireland |
CB134 | Irish Wolfhound | Calm, dignified, kindly; courageous but not aggressive | 81.3 cm minimum (male), 76.2 cm minimum (female) | 54.4 kg (male), 47.6 kg (female) | Ireland |
CB144 | Hungarian Komondor | Dignified, brave, protective, steadfastly loyal | 69.9 minimum cm (male), 64.8 minimum cm (female) | 45.4 kg or more (male), 36.3 kg or more (female) | Hungary |
CB147 | Labrador Retriever | Friendly and outgoing, Labs play well with others | 57.2-62.2 cm (male), 54.6-59.7 cm (female) | 29.5-36.3 kg (male), 24.9-31.8 kg (female) | Canada, United Kingdom (England) |
CB175 | Otterhound | Even-Tempered, amiable, boisterous | 68.6 cm (male), 61 cm (female) | 52.2 kg (male), 36.3 kg (female) | United Kingdom (England) |
CB205 | Rottweiler | Reserved with strangers and affectionate and loyal with his family. | 61-68.6 cm (male), 55.9-63.5 cm (female) | 49.9-59 kg (male), 34.9-49.9 kg (female) | Germany |
CB213 | Scottish Deerhound | Dignified, gentle, polite; quietly intelligent and perceptive | 76.2-81.3 cm (male), 71.1 cm & up (female) | 38.6-49.9 kg (male), 34-43.1 kg (female) | United Kingdom (Scotland) |
CB232 | St. Bernard | Friendly, patient, outgoing; known as a great “nanny dog” for kids | 71.1-76.2 cm (males), 66-71.1 cm (female) | 63.5-81.6 kg (male), 54.4-63.5 kg (female) | Italy, Switzerland |
CB252 | Weimaraner | Friendly, fearless, alert, obedient | 63.5-68.6 cm (male), 58.4-63.5 cm (female) | 31.8-40.8 kg (male), 24.9-34 kg (female) | Germany |
CB269 | Standard Poodle | Intelligent and quick-to-please | 56-66 cm |
2017 |
Belanger,J.M.,Bellumori,T.P.,Bannasch,D.L.,Famula,T.R.,Oberbauer,A.M.: :
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2017 |
Harkey,M.A.,Villagran,A.M.,Venkataraman,G.M.,Leisenring,W.M.,Hullar,M.A.J.,Torok-Storb,B.J.: :
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2017 |
O'Neill,D.G.,Case,J.,Boag,A.K.,Church,D.B.,McGreevy,P.D.,Thomson,P.C.,Brodbelt,D.C.: :
Gastric dilation-volvulus in dogs attending UK emergency-care veterinary practices: prevalence, risk factors and survival. J Small Anim Pract 58:629-638, 2017. Pubmed reference: 28833166 . DOI: 10.1111/jsap.12723 . |
2016 |
Tomlinson,A.W.,Lillis,S.M.,German,A.J.,Burrow,R.D.: :
Pyloric localisation in 57 dogs of breeds susceptible to gastric dilatation-volvulus in the UK using computed tomography. Vet Rec :, 2016. Pubmed reference: 27784838 . DOI: 10.1136/vr.103853 . |
2016 |
Ullmann,B.,Seehaus,N.,Hungerbühler,S.,Meyer-Lindenberg,A.: :
Gastric dilatation volvulus: a retrospective study of 203 dogs with ventral midline gastropexy. J Small Anim Pract 57:18-22, 2016. Pubmed reference: 26459100 . DOI: 10.1111/jsap.12406 . |
2015 |
Jen,C.C.,Wang,H.C.,Lin,J.L.,Chen,K.S.: :
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2015 |
Oberbauer,A.M.,Belanger,J.M.,Bellumori,T.,Bannasch,D.L.,Famula,T.R.: :
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2015 |
Uhrikova,I.,Rauserova-Lexmaulova,L.,Rehakova,K.,Scheer,P.,Doubek,J.: :
C-reactive protein and high mobility group box 1 in dogs with gastric dilatation and volvulus. J Vet Emerg Crit Care (San Antonio) :, 2015. Pubmed reference: 26088834 . DOI: 10.1111/vec.12324 . |
2014 |
Allen,P.,Paul,A.: :
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2014 |
Bell,J.S.: :
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2014 |
Bruchim,Y.,Kelmer,E.: :
Postoperative management of dogs with gastric dilatation and volvulus. Top Companion Anim Med 29:81-5, 2014. Pubmed reference: 25496926 . DOI: 10.1053/j.tcam.2014.09.003 . |
2014 |
Gazzola,K.M.,Nelson,L.L.: :
The relationship between gastrointestinal motility and gastric dilatation-volvulus in dogs. Top Companion Anim Med 29:64-6, 2014. Pubmed reference: 25496922 . DOI: 10.1053/j.tcam.2014.09.006 . |
2014 |
Mooney,E.,Raw,C.,Hughes,D.: :
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2014 |
Rozanski,E.,Sharp,C.: :
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2014 |
Sharp,C.R.,Rozanski,E.A.: :
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2014 |
Spinella,G.,Cinti,F.,Pietra,M.,Capitani,O.,Valentini,S.: :
A case report of percutaneous endoscopic gastrostomy left-side gastropexy to resolve a recurrent gastric dilatation in a dog previously treated with right-side gastropexy for gastric dilatation volvulus. Top Companion Anim Med 29:113-6, 2014. Pubmed reference: 25813852 . DOI: 10.1053/j.tcam.2014.12.001 . |
2013 |
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2013 |
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2013 |
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2013 |
Tubby,K.G.: :
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2013 |
VanKruiningen,H.J.,Gargamelli,C.,Havier,J.,Frueh,S.,Jin,L.,Suib,S.: :
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2012 |
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Evaluation of splenectomy as a risk factor for gastric dilatation-volvulus. J Am Vet Med Assoc 241:461-6, 2012. Pubmed reference: 22852571 . DOI: 10.2460/javma.241.4.461 . |
2012 |
Hendriks,M.M.,Hill,K.E.,Cogger,N.,Jones,B.R.,Cave,N.J.: :
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2012 |
Israeli,I.,Steiner,J.,Segev,G.,Kass,P.H.,Suchodolski,J.S.,Sattasathuchana,P.,Bruchim,Y.,Yudelevitch,S.,Aroch,I.: :
Serum pepsinogen-A, canine pancreatic lipase immunoreactivity, and C-reactive protein as prognostic markers in dogs with gastric dilatation-volvulus. J Vet Intern Med 26:920-8, 2012. Pubmed reference: 22594637 . DOI: 10.1111/j.1939-1676.2012.00940.x . |
2012 |
Pipan,M.,Brown,D.C.,Battaglia,C.L.,Otto,C.M.: :
An Internet-based survey of risk factors for surgical gastric dilatation-volvulus in dogs. J Am Vet Med Assoc 240:1456-62, 2012. Pubmed reference: 22657929 . DOI: 10.2460/javma.240.12.1456 . |
2010 |
Evans,K.M.,Adams,V.J.: :
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2010 |
Goldhammer,M.A.,Haining,H.,Milne,E.M.,Shaw,D.J.,Yool,D.A.: :
Assessment of the incidence of GDV following splenectomy in dogs. J Small Anim Pract 51:23-8, 2010. Pubmed reference: 20137005 . DOI: 10.1111/j.1748-5827.2009.00844.x . |
2009 |
Adamik,K.N.,Burgener,I.A.,Kovacevic,A.,Schulze,S.P.,Kohn,B.: :
Myoglobin as a prognostic indicator for outcome in dogs with gastric dilatation-volvulus. J Vet Emerg Crit Care (San Antonio) 19:247-53, 2009. Pubmed reference: 19691509 . DOI: 10.1111/j.1476-4431.2009.00421.x . |
2009 |
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2009 |
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2008 |
Moore,G.E.,Levine,M.,Anderson,J.D.,Trapp,R.J.: :
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2005 |
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2003 |
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2003 |
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2003 |
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2003 |
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2002 |
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2001 |
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2000 |
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2000 |
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2000 |
Glickman,L.T.,Glickman,N.W.,Schellenberg,D.B.,Raghavan,M.,Lee,T.L.: :
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2000 |
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1999 |
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1999 |
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1998 |
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1998 |
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1998 |
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