Expression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease
Release date:
2024-02-08
Description:
IgG4-related disease has been manifested with fibrosis, inflammation and deregulated metabolism clinical symptoms. In this study, we have investigated the molecular mechanism of the aforementioned clinical symptoms with PBMC from IgG4-RD patients, IgG4 cells lines and USP25 KO mice. By using RNA-seq, we have identified that USP25 controls the symptoms via several pathways as the central hub.
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Organization: School of Basic Medicine, Huazhong University of Science and Technology
Submission date: 2024-02-06
Requests: -
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