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HRA000867
   HRA000867.xlsx
Title:
The first report of NUP214-ABL1 fusion gene in acute myeloid leukemia patient detected by next-generation sequencing
Release date:
2021-05-27
Description:
The NUP214-ABL1 is a constitutively active tyrosine kinase that is found in 6% of T-cell acute lymphoblastic leukemia (T-ALL) patients; however the NUP214-ABL1 fusion in acute myeloid leukemia (AML) has not yet been reported. Up to now, the sensitivity of NUP214-ABL1-positive patients to tyrosine kinase inhibitor (TKI) is still controversial. Here we report the first case of an AML patient with NUP214-ABL1 fusion gene. The patient was successfully treated with conventional AML chemotherapy regimens. Identification of additional AML patients with NUP214-ABL1 fusion gene will provide treatment experience and prognostic evaluation.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA005089
Study type:
Disease Study
Disease name:
acute myeloid leukemia
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC000536
DAC name:
Jie Jin
Contact person:
Wang Huanping
Email:
whpi@163.com
Description:
Professor, Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University
Individuals & samples
Files
Request Data
Submitter:   Jin Jie / jiej0503@zju.edu.cn
Organization:   the First Affiliated Hospital, College of Medicine, Zhejiang University
Submission date:   2021-05-14
Requests:   -