Whole genome sequencing based mutational scanning in Klinefelter Syndrome patients
Release date:
2021-03-23
Description:
Current understanding holds that Klinefelter syndrome (KS) is not inherited, but oc-curs randomly during meiosis. Whether there is any genetic basis for the origin of KS is unknown.To study the potential genetic basis for paternal-origin KS, we performed WES in 108 unrelated KS patients with the classical 47, XXY karyotype.
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HRA000736.xlsx