Longitudinal peripheral blood transcriptional analysis reveals molecular signatures of disease progression in COVID-19 patients
Release date:
2021-02-25
Description:
Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with some patients can develop severe illness or even death. Disease severity has been associated with increased levels of pro-inflammatory cytokines and lymphopenia. To elucidate the atlas of peripheral immune response and pathways that might lead to immunopathology during COVID-19 disease course, we performed a peripheral blood RNA sequencing analysis of samples collected from the symptom onset to full recovery.
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