Mutational patterns are correlated with malignancy of early stage lung adenocarcinoma in multiple pulmonary nodules
Release date:
2020-12-18
Description:
We showed a developing pattern of quantity (the number of mutations/mutated genes) and quality (the extent of protein structural changes) in early stages of lung adenocarcinoma, as well as a stronger converging tendency in cell proliferation and survival related pathways and functions. Altogether, this study provides a new perspective for comprehension of genomic mutational data and might shed new light on deciphering the molecular evolution of early stage lung adenocarcinoma.
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Shenzhen People's Hospital was formerly Bao'an Country Health Center. It is now the largest modern hospital in the city, with advanced equipment, outstanding staff, state-of-the-art scientific research, top education and medical training, and it provides people with comprehensive medical services.
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HRA000465.xlsx