Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database information

piRBase (piRNA database)

General information

Description: a web resource assisting piRNA functional study
Year founded: 2014
Last update: 2014-11-01
Version: v1.0
Accessibility:
Manual:
Accessible
Real time : Checking...
Country/Region: China
Data type:
RNA
Data object:
NA
Database category:
Major organism:
NA
Keywords:

Contact information

University/Institution: Institute of Biophysics, Chinese Academy of Sciences
Address: Beijing 100101, China
City: Beijing
Province/State:
Country/Region: China
Contact name (PI/Team): Shunmin He
Contact email (PI/Helpdesk): heshunmin@ibp.ac.cn

Record metadata

Created on: 2015-06-20
Curated by:
Dong Zou [2019-09-14]
Dong Zou [2019-01-04]
Lina Ma [2018-06-14]
Shixiang Sun [2016-03-25]
Lina Ma [2016-03-10]
Mengwei Li [2016-02-20]
Shixiang Sun [2015-11-21]
Lina Ma [2015-06-29]
Shixiang Sun [2015-06-28]
Shixiang Sun [2015-06-26]

Ranking

All databases:
891/4587 (80.597%)
Gene genome and annotation:
299/1222 (75.614%)
891
Total Rank
47
Citations
7.833
z-index

Community reviews

Not Rated
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Word cloud

Publications

30371818
piRBase: a comprehensive database of piRNA sequences. [PMID: 30371818]
Wang J, Zhang P, Lu Y, Li Y, Zheng Y, Kan Y, Chen R, He S.

PIWI-interacting RNAs are a class of small RNAs that is most abundantly expressed in animal germline. Substantial research is going on to reveal the functions of piRNAs in the epigenetic and post-transcriptional regulation of transposons and genes. To collect and annotate these data, we developed piRBase, a database assisting piRNA functional study. Since its launch in 2014, piRBase has integrated 264 data sets from 21 organisms, and the number of collected piRNAs has reached 173 million. The latest piRBase release (v2.0, 2018) was more focused on the comprehensive annotation of piRNA sequences, as well as the increasing number of piRNAs. In addition, piRBase release v2.0 also contained the potential information of piRNA targets and disease related piRNA. All datasets in piRBase is free to access, and available for browse, search and bulk downloads at http://www.regulatoryrna.org/database/piRNA/.

Nucleic Acids Res. 2019:47(D1) | 12 Citations (from Europe PMC, 2020-08-01)
25425034
piRBase: a web resource assisting piRNA functional study. [PMID: 25425034]
Zhang P, Si X, Skogerbø G, Wang J, Cui D, Li Y, Sun X, Liu L, Sun B, Chen R, He S, Huang DW.

piRNAs are a class of small RNAs that is most abundantly expressed in the animal germ line. Presently, substantial research is going on to reveal the functions of piRNAs in the epigenetic and post-transcriptional regulation of transposons and genes. A piRNA database for collection, annotation and structuring of these data will be a valuable contribution to the field, and we have therefore developed the piRBase platform which integrates various piRNA-related high-throughput data. piRBase has the largest collection of piRNAs among existing databases, and contains at present 77 million piRNA sequences from nine organisms. Repeat-derived and gene-derived piRNAs, which possibly participate in the regulation of the corresponding elements, have been given particular attention. Furthermore, epigenetic data and reported piRNA targets were also collected. To our knowledge, this is the first piRNA database that systematically integrates epigenetic and post-transcriptional regulation data to support piRNA functional analysis. We believe that piRBase will contribute to a better understanding of the piRNA functions. Database URL: http://www.regulatoryrna.org/database/piRNA/ © The Author(s) 2014. Published by Oxford University Press.

Database (Oxford). 2014:2014() | 43 Citations (from Europe PMC, 2020-08-01)