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a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database information

LncBook (a curated knowledgebase of human long non-coding RNAs)

General information

Description: LncBook is a curated knowledgebase of human lncRNAs that features a comprehensive collection of human lncRNAs and systematic curation of lncRNAs by multi-omics data integration, functional annotation and disease association. The current implementation of LncBook houses a large number of 270,044 lncRNAs and includes 1,867 featured lncRNAs with 3,762 lncRNA-function associations.
Year founded: 2018
Last update: 2018
Version: v1.0
Accessibility:
Manual:
Accessible
Real time : Checking...
Country/Region: China
Data type:
RNA
Data object:
Database category:
Major organism:
Keywords:

Contact information

University/Institution: Beijing Institute of Genomics, Chinese Academy of Sciences
Address: No. 1 Beichen West Road, Chaoyang District, Beijing, China
City: Beijing
Province/State:
Country/Region: China
Contact name (PI/Team): Lina Ma
Contact email (PI/Helpdesk): malina@big.ac.cn

Related Database

Record metadata

Created on: 2019-03-08
Curated by:
Dong Zou [2019-12-03]
Lina Ma [2019-03-08]
Dong Zou [2019-03-08]

Ranking

All databases:
910/4656 (80.477%)
Gene genome and annotation:
304/1237 (75.505%)
910
Total Rank
8
Citations
8
z-index

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Not Rated
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Word cloud

Publications

30329098
LncBook: a curated knowledgebase of human long non-coding RNAs. [PMID: 30329098]
Ma L, Cao J, Liu L, Du Q, Li Z, Zou D, Bajic VB, Zhang Z.

Long non-coding RNAs (lncRNAs) have significant functions in a wide range of important biological processes. Although the number of known human lncRNAs has dramatically increased, they are poorly annotated, posing great challenges for better understanding their functional significance and elucidating their complex functioning molecular mechanisms. Here, we present LncBook (http://bigd.big.ac.cn/lncbook), a curated knowledgebase of human lncRNAs that features a comprehensive collection of human lncRNAs and systematic curation of lncRNAs by multi-omics data integration, functional annotation and disease association. In the present version, LncBook houses a large number of 270 044 lncRNAs and includes 1867 featured lncRNAs with 3762 lncRNA-function associations. It also integrates an abundance of multi-omics data from expression, methylation, genome variation and lncRNA-miRNA interaction. Also, LncBook incorporates 3772 experimentally validated lncRNA-disease associations and further identifies a total of 97 998 lncRNAs that are putatively disease-associated. Collectively, LncBook is dedicated to the integration and curation of human lncRNAs as well as their associated data and thus bears great promise to serve as a valuable knowledgebase for worldwide research communities.

Nucleic Acids Res. 2019:47(D1) | 8 Citations (from Europe PMC, 2020-08-08)