a catalog of biological databases
|Description:||As part of our research scanning for evolutionary signals in HapMap Phase II and Phase III datasets, we built SNP@Evolution as a multi-aspect database focused on positive selection.|
|University/Institution:||Beijing Institute of Genomics, Chinese Academy of Sciences|
|Address:||1 Beichen West Road, Chaoyang District, Beijing 100101, China|
|Contact name (PI/Team):||Changqing Zeng|
|Contact email (PI/Helpdesk):||firstname.lastname@example.org|
SNP@Evolution: a hierarchical database of positive selection on the human genome. [PMID: 19732458]
BACKGROUND: Positive selection is a driving force that has shaped the modern human. Recent developments in high throughput technologies and corresponding statistics tools have made it possible to conduct whole genome surveys at a population scale, and a variety of measurements, such as heterozygosity (HET), FST, and Tajima's D, have been applied to multiple datasets to identify signals of positive selection. However, great effort has been required to combine various types of data from individual sources, and incompatibility among datasets has been a common problem. SNP@Evolution, a new database which integrates multiple datasets, will greatly assist future work in this area.