Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database information

LSD 3.0 (Leaf Senescence DataBase)

General information

Description: To facilitate the systematical research and comparative study of leaf senescence,we constructed a database of leaf senescence (LSD 1.0,August 2011) to collect SAGs,mutants,phenotypes and literature references. We now update LSD to a new version LSD 2.0 (June,2013).
Year founded: 2011
Last update: 2019-08-01
Version: v3.0
Real time : Checking...
Country/Region: China
Data type:
Data object:
Database category:
Major organism:

Contact information

University/Institution: Beijing Institute of Genomics, Chinese Academy of Sciences
Address: Beijing 100871, China
City: Beijing
Province/State: Beijing
Country/Region: China
Contact name (PI/Team): Zhang Zhang
Contact email (PI/Helpdesk):

Related Database

Record metadata

Created on: 2015-06-20
Curated by:
Dong Zou [2019-12-07]
Dong Zou [2019-09-14]
Zhang Zhang [2019-06-21]
huma shireen [2018-08-30]
Lina Ma [2018-06-13]
Lina Ma [2018-02-05]
Chunlei Yu [2016-04-17]
Chunlei Yu [2016-04-01]
Chunlei Yu [2015-11-20]
Jian SA [2015-07-01]
Chunlei Yu [2015-06-29]


All databases:
915/4656 (80.369%)
Genotype phenotype and variation:
123/628 (80.573%)
55/295 (81.695%)
Total Rank

Community reviews

Not Rated
Data quality & quantity:
Content organization & presentation
System accessibility & reliability:

Word cloud


Construction of the Leaf Senescence Database and Functional Assessment of Senescence-Associated Genes. [PMID: 27987180]
Li Z, Zhao Y, Liu X, Jiang Z, Peng J, Jin J, Guo H, Luo J.

Leaf senescence is the last phase of plant development and a highly coordinated process regulated by a large number of senescence-associated genes (SAGs). By broad literature survey, we constructed a leaf senescence database (LSD) in 2011 and updated it to Version 2.0 in 2014 ( and ) which contains a total of 5357 genes and 324 mutants from 44 species. These SAGs were retrieved based on genetic, genomic, proteomic, physiological, or other experimental evidence and were classified into different categories according to their functions in leaf senescence or morphological phenotype of mutants. To provide comprehensive information for SAGs, we made extensive annotation by both manual and computational approaches. In addition, we predicted putative orthologues of the SAGs in other species. LSD has a user-friendly interface to allow users to make text queries or BLAST searches and to download SAGs sequences for local analysis. Functional analyses of putative SAGs reveal that WRKY75, AZF2, NAC16, and WRKY26 are positive regulators of leaf senescence, while MKP2 and CTR1 perform negative regulation to leaf senescence. This database has been served as a valuable resource for basic research on the function of SAGs and evolution of plant leaf senescence, as well as for the exploration of genetic traits in agronomically important plants.

Methods Mol Biol. 2017:1533() | 5 Citations (from Europe PMC, 2020-08-08)
LSD 2.0: an update of the leaf senescence database. [PMID: 24185698]
Li Z, Zhao Y, Liu X, Peng J, Guo H, Luo J.

This manuscript describes an update of the leaf senescence database (LSD) previously featured in the 2011 NAR Database Issue. LSD provides comprehensive information concerning senescence-associated genes (SAGs) and their corresponding mutants. We have made extensive annotations for these SAGs through both manual and computational approaches. Recently, we updated LSD to a new version LSD 2.0 (, which contains 5356 genes and 322 mutants from 44 species, an extension from the previous version containing 1145 genes and 154 mutants from 21 species. In the current version, we also included several new features: (i) Primer sequences retrieved based on experimental evidence or designed for high-throughput analysis were added; (ii) More than 100 images of Arabidopsis SAG mutants were added; (iii) Arabidopsis seed information obtained from The Arabidopsis Information Resource (TAIR) was integrated; (iv) Subcellular localization information of SAGs in Arabidopsis mined from literature or generated from the SUBA3 program was presented; (v) Quantitative Trait Loci information was added with links to the original database and (vi) New options such as primer and miRNA search for database query were implemented. The updated database will be a valuable and informative resource for basic research of leaf senescence and for the manipulation of traits of agronomically important plants.

Nucleic Acids Res. 2014:42(Database issue) | 29 Citations (from Europe PMC, 2020-08-08)
LSD: a leaf senescence database. [PMID: 21097471]
Liu X, Li Z, Jiang Z, Zhao Y, Peng J, Jin J, Guo H, Luo J.

By broad literature survey, we have developed a leaf senescence database (LSD, that contains a total of 1145 senescence associated genes (SAGs) from 21 species. These SAGs were retrieved based on genetic, genomic, proteomic, physiological or other experimental evidence, and were classified into different categories according to their functions in leaf senescence or morphological phenotypes when mutated. We made extensive annotations for these SAGs by both manual and computational approaches, and users can either browse or search the database to obtain information including literatures, mutants, phenotypes, expression profiles, miRNA interactions, orthologs in other plants and cross links to other databases. We have also integrated a bioinformatics analysis platform WebLab into LSD, which allows users to perform extensive sequence analysis of their interested SAGs. The SAG sequences in LSD can also be downloaded readily for bulk analysis. We believe that the LSD contains the largest number of SAGs to date and represents the most comprehensive and informative plant senescence-related database, which would facilitate the systems biology research and comparative studies on plant aging.

Nucleic Acids Res. 2011:39(Database issue) | 37 Citations (from Europe PMC, 2020-08-08)