| Accession |
PRJCA001861 |
| Title |
Modulation of Auxin Signaling and Development by Polyadenylation Machinery |
| Relevance |
Model organism |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Arabidopsis thaliana
|
| Description |
We observed that PASs in transcripts from approximately 2,400 genes were shifted in the cstf77-2 mutant. Moreover, most of the PAS shifts were from proximal to distal sites. Auxin treatment also caused PAS shifts in transcripts from a small number of genes. Several auxin signaling or homeostasis genes had different PASs in their transcripts in the cstf77-2 mutant. The expression levels of AUXIN RESISTANT 2/INDOLE-3-ACETIC ACID 7 were significantly increased in the cstf77-2 mutant, which can partially account for the auxin resistance phenotype of this mutant. Our results demonstrate that AtCstF77 plays pleiotropic and critical roles in Arabidopsis development. Moreover, disruption of AtCstF64, another component of the polyadenylation machinery, led to developmental defects and reduced auxin response, similar to those of the cstf77-2 mutant. We conclude that AtCstF77 affects auxin responses, likely by controlling PAS selection of transcripts of some auxin signaling components. |
| Sample scope |
plant tissue |
| Release date |
2019-10-22 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 30487141
|
Modulation of Auxin Signaling and Development by Polyadenylation Machinery
|
Plant Physiology
|
10.1104/pp.18.00782
|
2019
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
31270330
|
|
|
|
| Submitter |
Jing
Sun (jsun@genetics.ac.cn)
|
| Organization |
Institute of genetics and developmental biology, Chinese Academy of Sciences |
| Submission date |
2019-10-22 |
