Accession PRJCA001517
Title Time-course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-infected Human Gingival Fibroblasts
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description We implemented a time-series experiment and performed an RNA-Seq analysis to explore gene expression profiles during the process of F. nucleatum infection in GFs. We computationally identified several U.S. Food and Drug Administration (FDA)-approved drugs, which could protect the F. nucleatum infected GFs via a co-expression-based drug repositioning approach.
Sample scope Multiisolate
Release date 2019-09-12
Publication
PubMed ID Article title Journal name DOI Year
31608279 Time-Course Transcriptome Analysis for Drug Repositioning in -Infected Human Gingival Fibroblasts Frontiers in Cell and Developmental Biology 10.3389/fcell.2019.00204 2019
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) Major Program 81630072
National Natural Science Foundation of China (NSFC) Young Scientists Fund 31701155
Ministry of Science and Technology of the People's Republic of China (MOST) The National Key Research and Development Program of China 2017YFC0908403
Ministry of Science and Technology of the People's Republic of China (MOST) The National Key Research and Development Program of China 2017YFC0114001
Ministry of Science and Technology of the People's Republic of China (MOST) The National Key Research and Development Program of China 2017YFC0908400
Submitter Wenyan    Kang  (943818034@qq.com)
Organization Shandong University
Submission date 2019-06-18

Project Data

Resource name Description
BioSample (54)  show -
GSA (1) -
CRA001739 Time-course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-infected Human Gingival Fibroblasts