Accession |
PRJCA001517 |
Title |
Time-course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-infected Human Gingival Fibroblasts |
Relevance |
Medical |
Data types |
Transcriptome or Gene expression
|
Organisms |
Homo sapiens
|
Description |
We implemented a time-series experiment and performed an RNA-Seq analysis to explore gene expression profiles during the process of F. nucleatum infection in GFs. We computationally identified several U.S. Food and Drug Administration (FDA)-approved drugs, which could protect the F. nucleatum infected GFs via a co-expression-based drug repositioning approach. |
Sample scope |
Multiisolate |
Release date |
2019-09-12 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
31608279
|
Time-Course Transcriptome Analysis for Drug Repositioning in -Infected Human Gingival Fibroblasts
|
Frontiers in Cell and Developmental Biology
|
10.3389/fcell.2019.00204
|
2019
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
Major Program
|
81630072
|
|
National Natural Science Foundation of China (NSFC)
|
Young Scientists Fund
|
31701155
|
|
Ministry of Science and Technology of the People's Republic of China (MOST)
|
The National Key Research and Development Program of China
|
2017YFC0908403
|
|
Ministry of Science and Technology of the People's Republic of China (MOST)
|
The National Key Research and Development Program of China
|
2017YFC0114001
|
|
Ministry of Science and Technology of the People's Republic of China (MOST)
|
The National Key Research and Development Program of China
|
2017YFC0908400
|
|
|
Submitter |
Wenyan
Kang (943818034@qq.com)
|
Organization |
Shandong University |
Submission date |
2019-06-18 |