Accession |
PRJCA000857 |
Title |
Nuclear PTEN safeguards pre-mRNA splicing to link Golgi extension and secretion for its tumor suppressive role |
Relevance |
Medical |
Data types |
Raw sequence reads
|
Organisms |
Homo sapiens
|
Description |
Dysregulation of pre-mRNA alternative splicing (AS) is closely associated with cancers.In this project, we we report that nuclear PTEN interacts with the splicing machinery, spliceosome, to regulate its assembly and pre-mRNA splicing. |
Sample scope |
Single cell |
Release date |
2018-04-25 |
Submitter |
Shen
shao
ming (smshen01@sibs.ac.cn)
|
Organization |
Shanghai Jiaotong Universit School of Medicine |
Submission date |
2018-04-25 |