Accession PRJCA000857
Title Nuclear PTEN safeguards pre-mRNA splicing to link Golgi extension and secretion for its tumor suppressive role
Relevance Medical
Data types Raw sequence reads
Organisms Homo sapiens
Description Dysregulation of pre-mRNA alternative splicing (AS) is closely associated with cancers.In this project, we we report that nuclear PTEN interacts with the splicing machinery, spliceosome, to regulate its assembly and pre-mRNA splicing.
Sample scope Single cell
Release date 2018-04-25
Submitter Shen  shao  ming  (smshen01@sibs.ac.cn)
Organization Shanghai Jiaotong Universit School of Medicine
Submission date 2018-04-25

Project Data

Resource name Description
BioSample (6)  show -
GSA (1) -
CRA000899 Nuclear PTEN safeguards pre-mRNA splicing to link Golgi extension and secretion for its tumor suppressive role