| Accession |
PRJCA000476 |
| Title |
whole exon sequencing of chemorefractory pediatric AML |
| Relevance |
Medical |
| Data types |
Exome
|
| Organisms |
Homo sapiens
|
| Description |
Despite substantial improvement of treatment outcome in pediatric acute myeloid leukemia (AML), chemotherapy resistance remains to be a major concern. While molecular basis behind therapeutic failure was intensely interrogated, genomic alteration of chemotherapy resistance remains poorly characterized in pediatric AML. Here, we performed whole exon sequencing to identify gene mutations associated with primary and secondary chemo-resistance in pediatric AML. |
| Sample scope |
Monoisolate |
| Release date |
2017-12-17 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 29253671
|
Whole exome sequencing identifies novel mutations of epigenetic regulators in chemorefractory pediatric acute myeloid leukemia.
|
Leukemia Research
|
10.1016/j.leukres.2017.12.001
|
2017
|
|
|
| Submitter |
Di
Zhan (zhandi@big.ac.cn)
|
| Organization |
Beijing Institute of Genomics |
| Submission date |
2017-06-14 |
