History
With the gradual aging of the global population, the need to research and find the keys to healthy aging is ever more critical and takes on new urgency. Aging is a complex process, influenced by environmental factors, genetic and epigenetic regulations, post-translational modifications, metabolism, microbiome, lifestyle, and other factors. Recently, high-throughput omics technologies (including genomics, transcriptomics, epigenomics, metabolomics, proteomics, pharmacogenomics and metagenomics) have been widely applied to aging studies, facilitating large-scale profiling of aging-associated molecular changes and regulatory states. In addition, emerging methods have allowed us to probe aging at the single-cell resolution, providing integrated multi-dimensional data at an unprecedented scale and depth. To date, a growing volume of valuable aging-related data necessitates an open, integrative database to support new lines of aging research. Aging Atlas is a project that began in 2019 and aims to provide a wide range of life science researchers with valuable resources and allow access to large-scale gene expression and regulation datasets created by a range of high-throughput omics technologies.
