e.g. IL6;  SIRT6; 

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1 Vitamin C
2 Quercetin
3 Metformin

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Nicotinamide Riboside:

Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging. Recruit

Geroprotective Compounds

  The pharmacogenomics module focuses on geroprotectors. Currently, the module has a list of hundreds of compounds and contains omics datasets from drug therapy analysis (both in vivo and in vitro), revealing changes in gene regulation and expression caused by the supplementation of specific lifespan/healthspan-extending drugs.

Compounds NameOrganismAging PhenotypeRNA-seq
Alpha-phenyl-N-t-butyl-nitroneHomo sapiens (cell culture) Extended Lifespan Not Available
Alpha-phenyl-N-t-butyl-nitroneMus musculus Extended Lifespan Not Available
Antimycin ACaenorhabditis elegansExtended Lifespan Not Available
Antimycin ASaccharomyces cerevisiae (chronological) Shortened Lifespan Not Available
Acacetin 7-O-alpha-l-rhamnopyranosyl (1_2) beta-D-xylopyranosideCaenorhabditis elegansExtended Lifespan  Not Available
AcarboseMus musculusExtended Lifespan  Not Available
AcarboseMus musculusExtended Lifespan  Not Available
AcetaminophenCaenorhabditis elegansExtended Lifespan  Not Available
AcetaminophenMus musculusExtended Lifespan  Not Available
Acetic AcidCaenorhabditis elegansExtended Lifespan  Not Available
Acticoa powderRattus norvegicusExtended Lifespan  Not Available
AG-490Drosophila melanogasterExtended Lifespan  Not Available
AgmatineCaenorhabditis elegansExtended Lifespan  Not Available
AlanineCaenorhabditis elegansExtended Lifespan  Not Available
AllantoinCaenorhabditis elegansExtended Lifespan  Not Available
Alpha-ketoglutarateCaenorhabditis elegansExtended Lifespan  Not Available
Alpha-lipoic acidDrosophila melanogasterExtended Lifespan  Not Available
Alpha-lipoic acidCaenorhabditis elegansExtended Lifespan  Not Available
AMN082Caenorhabditis elegansExtended Lifespan  Not Available
AmoxapineCaenorhabditis elegansExtended Lifespan  Not Available
Amperozide hydrochlorideCaenorhabditis elegansExtended Lifespan  Not Available
AmpicillinCaenorhabditis elegansExtended Lifespan  Not Available
ArbutinCaenorhabditis elegansExtended Lifespan  Not Available
ArctigeninCaenorhabditis elegansExtended Lifespan  Not Available
ArctiinCaenorhabditis elegansExtended Lifespan  Not Available
ArginineCaenorhabditis elegansExtended Lifespan  Not Available
Argyreia boseanaCaenorhabditis elegansShortened LifespanNot Available
ArseniteCaenorhabditis elegansExtended Lifespan Not Available
AspirinMus musculusExtended Lifespan Not Available
AspirinCaenorhabditis elegansExtended Lifespan Not Available
AspirinAcheta domesticusExtended Lifespan Not Available
AstaxanthinCaenorhabditis elegansExtended Lifespan Not Available
Astragalus membranaceus polysaccharideCaenorhabditis elegansExtended Lifespan Not Available
Astragalus polysaccharideCaenorhabditis elegansExtended Lifespan Not Available
AU701Drosophila melanogasterExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
BacitracinCaenorhabditis elegansExtended Lifespan Not Available
BaicaleinCaenorhabditis elegansExtended Lifespan Not Available
Beta-alanineCaenorhabditis elegansExtended Lifespan Not Available
Beta-caryophylleneCaenorhabditis elegansExtended Lifespan Not Available
Beta-EstradiolCaenorhabditis elegansExtended Lifespan Not Available
Beta-Guanidinopropionic acidDrosophila melanogasterExtended Lifespan Not Available
BetaineCaenorhabditis elegansExtended Lifespan Not Available
BezafibrateCaenorhabditis elegansExtended Lifespan Not Available
Bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)-decandioateAeolosoma virideExtended Lifespan Not Available
Blueberry polyphenolsCaenorhabditis elegansExtended Lifespan Not Available
Blueberry polyphenolsDrosophila melanogasterExtended Lifespan Not Available
Branched-Chain Amino AcidsMus musculusExtended Lifespan Not Available
BRL 15572Caenorhabditis elegansExtended Lifespan Not Available
BRL 50481Caenorhabditis elegansExtended Lifespan Not Available
BTCP hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
BuforminRattus norvegicusExtended Lifespan Not Available
ButeinSaccharomyces cerevisiae Extended Lifespan Not Available
Butylated hydroxyanisoleZaprionus paravittigerExtended Lifespan Not Available
Butylated hydroxyanisoleCaenorhabditis elegansExtended Lifespan Not Available
Butylated hydroxytolueneDrosophila bipectinata Extended Lifespan Not Available
Butylated hydroxytolueneMus musculusExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
C60Rattus norvegicusExtended Lifespan Not Available
Caffeic acid phenethylesterCaenorhabditis elegansExtended Lifespan Not Available
CaffeineSaccharomyces cerevisiaeExtended Lifespan Not Available
CaffeineCaenorhabditis elegansExtended Lifespan Not Available
Calcium lactateDrosophila melanogasterExtended Lifespan Not Available
CaprylateCaenorhabditis elegansExtended Lifespan Not Available
Carbonylcyanide-3-chlorophenylhydrazoneCaenorhabditis elegansExtended Lifespan Not Available
CarnosineDrosophila melanogasterExtended Lifespan Not Available
CarnosineCaenorhabditis elegansExtended Lifespan Not Available
CatechinCaenorhabditis elegansExtended Lifespan Not Available
CelastrolCaenorhabditis elegansExtended Lifespan Not Available
CelecoxibCaenorhabditis elegansExtended Lifespan Not Available
Chicoric acidCaenorhabditis elegansExtended Lifespan Not Available
ChloramphenicolCaenorhabditis elegansExtended Lifespan Not Available
Chlorprothixene hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
Ciclopirox olamineCaenorhabditis elegansExtended Lifespan Not Available
CinnarizineCaenorhabditis elegansExtended Lifespan Not Available
Cis-(Z)-Flupenthixol dihydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
CitrateMytilina brevispinaExtended Lifespan Not Available
ClofibrateCaenorhabditis elegansExtended Lifespan Not Available
CocoaDrosophila melanogasterExtended Lifespan Not Available
Coenzyme Q10Caenorhabditis elegansExtended Lifespan Not Available
Copper gluconateMus musculusShortened LifespanNot Available
Cordyceps sinensis oral liquidDrosophila melanogasterExtended Lifespan Not Available
Cortexolone maleateCaenorhabditis elegansExtended Lifespan Not Available
CortisoneAsplanchna brightwelliExtended Lifespan Not Available
CreatineMus musculusExtended Lifespan Not Available
CreatineCaenorhabditis elegansShortened LifespanNot Available
CU701Drosophila melanogasterExtended Lifespan Not Available
CurareAsplanchna brightwelliExtended Lifespan Not Available
CurcuminDrosophila melanogasterExtended Lifespan Not Available
CurcuminCaenorhabditis elegansExtended Lifespan Not Available
Cyclosporin ACaenorhabditis elegansExtended Lifespan Not Available
Cynomorium songaricum Rupr.Drosophila melanogasterExtended Lifespan Not Available
Cyproterone acetateCaenorhabditis elegansExtended Lifespan Not Available
CysteineCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
Dafadine-ACaenorhabditis elegansExtended Lifespan Not Available
D-alanineCaenorhabditis elegansExtended Lifespan Not Available
DanazolCaenorhabditis elegansExtended Lifespan Not Available
DAPHCaenorhabditis elegansExtended Lifespan Not Available
D-aspartateCaenorhabditis elegansExtended Lifespan Not Available
Dauer-inducing PheromoneCaenorhabditis elegansExtended Lifespan Not Available
D-beta-hydroxybutyrateCaenorhabditis elegansExtended Lifespan Not Available
D-chiro-inositolDrosophila melanogasterExtended Lifespan Not Available
Dehydroabietic acidCaenorhabditis elegansExtended Lifespan Not Available
Demeclocycline hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
DeprenylRattus norvegicus Extended Lifespan Not Available
DeprenylMesocricetus auratus Extended Lifespan Not Available
DeprenylCanis lupus familiaris Extended Lifespan Not Available
DeprenylMus musculus Extended Lifespan Not Available
DeprenylRattus norvegicus Shortened Lifespan Not Available
D-glucosamineCaenorhabditis elegansExtended Lifespan Not Available
D-glucosamineMus musculusExtended Lifespan Not Available
D-glucoseSaccharomyces cerevisiae Extended Lifespan Not Available
D-glutamateCaenorhabditis elegansExtended Lifespan Not Available
D-glycerolSaccharomyces cerevisiaeExtended Lifespan Not Available
D-glycerol Brachionus manjavacasExtended Lifespan /HealthspanNot Available
DhHP-6Caenorhabditis elegansExtended Lifespan Not Available
Diallyl trisulfideCaenorhabditis elegansExtended Lifespan Not Available
Dibromoacetic acidCaenorhabditis elegansExtended Lifespan Not Available
Dihydroergotamine methanesulfonateCaenorhabditis elegansExtended Lifespan Not Available
DigoxinCaenorhabditis elegansExtended Lifespan Not Available
DigoxinMus musculusExtended HealthspanNot Available
Diiodomethane Drosophila melanogaster Extended Lifespan Not Available
DimethylformamideCaenorhabditis elegansExtended Lifespan Not Available
DimethylsulfideCaenorhabditis elegansExtended Lifespan Not Available
DimethylsulfoxideCaenorhabditis elegansExtended Lifespan Not Available
Diphenylhydantoin Mus musculus Extended Lifespan Not Available
DL-isocitrateCaenorhabditis elegansExtended Lifespan Not Available
DL-lactateCaenorhabditis elegansExtended Lifespan Not Available
Doxazosin mesylateCaenorhabditis elegansExtended Lifespan Not Available
DoxycyclineCaenorhabditis elegansExtended Lifespan Not Available
Doxycycline hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
D-sorbitol Saccharomyces cerevisiaeExtended Lifespan Not Available
D-xylitolSaccharomyces cerevisiaeExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
Echinacea purpurea rootMus musculusExtended Lifespan Not Available
Edetate Calcium DisodiumMytilina brevispinaExtended Lifespan Not Available
Edetate Calcium DisodiumCaenorhabditis elegansExtended Lifespan Not Available
EDTA Mytilina brevispina var redunca Extended Lifespan Not Available
EGb 761 Caenorhabditis elegans Extended Lifespan Not Available
EGTA Mytilina brevispina var redunca Extended Lifespan Not Available
EliprodilCaenorhabditis elegansExtended Lifespan Not Available
Emblica officinalisDrosophila melanogasterExtended Lifespan Not Available
EpicatechinDrosophila melanogasterExtended Lifespan Not Available
Epigallocatechin-3-gallateCaenorhabditis elegansExtended Lifespan Not Available
Epigallocatechin-3-gallateRattus norvegicusExtended Lifespan Not Available
Epigallocatechin-3-gallateDrosophila melanogasterExtended Lifespan Not Available
EpitalonDrosophila melanogasterExtended Lifespan Not Available
EpithalaminMus musculusExtended Lifespan Not Available
EpithalaminDrosophila melanogasterExtended Lifespan Not Available
EpithalaminRattus norvegicusExtended Lifespan Not Available
Erbstatin analogDrosophila melanogasterExtended Lifespan Not Available
Erchen wanCaenorhabditis elegansExtended Lifespan Not Available
Ethidium bromideCaenorhabditis elegansExtended Lifespan Not Available
EthosuximideCaenorhabditis elegansExtended Lifespan Not Available
EthoxyquinMus musculusExtended Lifespan Not Available
EUK-134Musca domestica Shortened Lifespan Not Available
EUK-134Caenorhabditis elegans Extended Lifespan Not Available
EUK-134Aeolosoma virideExtended Lifespan Not Available
EUK-8Musca domestica Shortened Lifespan Not Available
EUK-8 Caenorhabditis elegans Extended Lifespan  Not Available
EverolimusDrosophila melanogasterExtended Lifespan  Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
FCCPCaenorhabditis elegansExtended Lifespan Not Available
FenofibrateCaenorhabditis elegansExtended Lifespan Not Available
Ferulsinaic acidCaenorhabditis elegansExtended Lifespan Not Available
FisetinDrosophila melanogasterExtended Lifespan Not Available
Fisetin Saccharomyces cerevisiaeExtended Lifespan Not Available
FumarateCaenorhabditis elegansExtended Lifespan Not Available
Folic acidCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
GalactoseDrosophila melanogasterShortened LifespanNot Available
GalactoseMusca domesticaShortened LifespanNot Available
GalactoseCaenorhabditis elegansExtended Lifespan Not Available
Gallic AcidCaenorhabditis elegansExtended Lifespan Not Available
Gamma-tocopherolCaenorhabditis elegansExtended Lifespan Not Available
Garlic extractDrosophila melanogasterExtended Lifespan Not Available
Garlic extractCaenorhabditis elegansExtended Lifespan Not Available
GeldanamycinCaenorhabditis elegansExtended Lifespan Not Available
GenisteinCaenorhabditis elegansExtended Lifespan Not Available
Ginkgo biloba extractCaenorhabditis elegansExtended Lifespan Not Available
Ginkgo biloba extractRattus norvegicusExtended Lifespan /HealthspanNot Available
GlaucarubinoneCaenorhabditis elegansExtended Lifespan Not Available
GluconateCaenorhabditis elegansExtended Lifespan Not Available
Gluconic acidDrosophila melanogasterExtended Lifespan Not Available
GlutathioneCaenorhabditis elegansExtended Lifespan Not Available
Glyceollin ISaccharomyces cerevisiaeExtended Lifespan Not Available
GlycineCaenorhabditis elegansExtended Lifespan Not Available
Green tea polyphenolsMus musculusExtended Lifespan Not Available
Green tea polyphenolsDrosophila melanogasterExtended Lifespan Not Available
Guanabenz acetateCaenorhabditis elegansExtended Lifespan Not Available
Guanfacine hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
Guduchi ChurnaDrosophila melanogasterExtended Lifespan Not Available
GYY4137Caenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
HA-1004Drosophila melanogasterExtended Lifespan Not Available
HA-1077Drosophila melanogasterExtended Lifespan Not Available
HesperidinSaccharomyces cerevisiaeExtended Lifespan Not Available
Hexahydro-sila-diphenidolCaenorhabditis elegansExtended Lifespan Not Available
HF-HQCaenorhabditis elegansExtended Lifespan Not Available
HistidineCaenorhabditis elegansExtended Lifespan Not Available
HomocysteineCaenorhabditis elegansExtended Lifespan Not Available
Huperzine ACaenorhabditis elegansExtended Lifespan  Not Available
HydralazineBrachionus manjavacasExtended Lifespan  Not Available
HydralazineCaenorhabditis elegansExtended Lifespan  Not Available
Hydrogen SulphideCaenorhabditis elegansExtended Lifespan  Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
IcariinMus musculusExtended Lifespan Not Available
IcariinCaenorhabditis elegansExtended Lifespan Not Available
IndirubinDrosophila melanogasterExtended Lifespan Not Available
IndolepropionamidePhilodina acuticornisExtended Lifespan Not Available
InositolCaenorhabditis elegansExtended Lifespan Not Available
IsoleucineCaenorhabditis elegansExtended Lifespan Not Available
IvabradineMus musculusExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
JugloneCaenorhabditis elegansExtended Lifespan Not Available
JH4Mus musculusExtended Lifespan /HealthspanNot Available
Compounds NameOrganismAging PhenotypeRNA-seq
KaempferolApis melliferaExtended Lifespan Not Available
KenpaulloneCaenorhabditis elegansExtended Lifespan Not Available
Ketanserin tartrateCaenorhabditis elegansExtended Lifespan Not Available
KN-93Drosophila melanogasterExtended Lifespan Not Available
Korean red ginseng tonicDrosophila melanogasterExtended Lifespan Not Available
Kinetin Zaprionus paravittiger Extended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
L- carnosine Homo sapiens (cell culture) Extended Lifespan Not Available
Lactic acidDrosophila melanogasterExtended Lifespan Not Available
LamotrigineDrosophila melanogasterExtended Lifespan Not Available
Lappaol CCaenorhabditis elegansExtended Lifespan Not Available
Lappaol FCaenorhabditis elegansExtended Lifespan Not Available
LargazoleHomo sapiens (cell culture) Extended Lifespan Not Available
L-deprenylRattus norvegicusExtended Lifespan Not Available
L-deprenylMesocricetus auratusExtended Lifespan Not Available
L-deprenylCanis lupus familiarisExtended Lifespan Not Available
LeucineCaenorhabditis elegansExtended Lifespan Not Available
LFM-A13Caenorhabditis elegansExtended Lifespan Not Available
L-Glu-L-Trp dipeptideRattus norvegicusExtended Lifespan Not Available
L-histidine methyl esterCaenorhabditis elegansExtended Lifespan Not Available
Lithium ChlorideCaenorhabditis elegansExtended Lifespan Not Available
Lithium ChlorideDrosophila melanogasterExtended Lifespan Not Available
Lithium ChlorideSaccharomyces cerevisiaeExtended Lifespan Not Available
Lithocholic acidSaccharomyces cerevisiaeExtended Lifespan Not Available
LonidamineCaenorhabditis elegansExtended Lifespan Not Available
LoratadineCaenorhabditis elegansExtended Lifespan Not Available
Loxapine succinateCaenorhabditis elegansExtended Lifespan Not Available
L-theanineCaenorhabditis elegansExtended Lifespan Not Available
LuteinDrosophila melanogasterExtended Lifespan Not Available
LY-165,163Caenorhabditis elegansExtended Lifespan Not Available
LY-294002Drosophila melanogasterExtended Lifespan Not Available
LY-294002Caenorhabditis elegansExtended Lifespan Not Available
LY-367,265Caenorhabditis elegansExtended Lifespan Not Available
LysineCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
M084Caenorhabditis elegansExtended Lifespan Not Available
Magnesium thiazolidine-4-carboxylic acid Aedes aegypti Extended Lifespan Not Available
MalateCaenorhabditis elegansExtended Lifespan Not Available
Marine collagen peptidesRattus norvegicusExtended Lifespan Not Available
MatairesinolCaenorhabditis elegansExtended Lifespan Not Available
MelatoninDrosophila melanogasterExtended Lifespan Not Available
MelatoninParamecium tetraureliaExtended Lifespan Not Available
MelatoninMus musculusExtended Lifespan Not Available
Melatonin Mus musculus Extended Lifespan Not Available
Melatonin Drosophila melanogaster Extended Lifespan Not Available
MetergolineCaenorhabditis elegansExtended Lifespan Not Available
MetforminRattus norvegicusExtended Lifespan Not Available
MetforminRattus norvegicus(cell culture)Extended Lifespan Not Available
MetforminCaenorhabditis elegansExtended Lifespan Not Available
MetforminDrosophila melanogasterExtended Lifespan Not Available
MetforminHomo sapiens (cell culture) Extended Lifespan Not Available
MetforminMus musculusExtended Lifespan /Healthspanview
MethionineCaenorhabditis elegansExtended Lifespan Not Available
Methionine Mus musculus Extended Lifespan Not Available
Methionine Zaprionus paravittiger Extended Lifespan Not Available
Methylene blueHomo sapiens (cell culture) Extended Lifespan Not Available
Methylergonovine maleateCaenorhabditis elegansExtended Lifespan Not Available
MetoprololMus musculusExtended Lifespan Not Available
MG132Mus musculusExtended Lifespan /HealthspanNot Available
MianserinCaenorhabditis elegansExtended Lifespan Not Available
MinocyclineDrosophila melanogasterExtended Lifespan Not Available
Minocycline hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
MorphineDrosophila melanogasterExtended Lifespan Not Available
MPTPCaenorhabditis elegansExtended Lifespan Not Available
Mulberry leaf polyphenolsCaenorhabditis elegansExtended Lifespan Not Available
MyricetinCaenorhabditis elegansExtended Lifespan Not Available
MyriocinSaccharomyces cerevisiaeExtended Lifespan Not Available
MyxothiazolCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
N-(2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamideCaenorhabditis elegansExtended Lifespan Not Available
N-(3-(aminomethyl)benzyl)acetamidineDrosophila melanogasterExtended Lifespan Not Available
N-acetylcysteine Drosophila melanogaster Extended Lifespan Not Available
N-acetylglucosamineCaenorhabditis elegansExtended Lifespan Not Available
N-acetyl-L-cysteineCaenorhabditis elegansExtended Lifespan Not Available
N-acetyl-L-cysteineMus musculusExtended Lifespan Not Available
N-acetyl-L-cysteineDrosophila melanogasterExtended Lifespan Not Available
Naftopidil dihydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
NaphthazarinCaenorhabditis elegansExtended Lifespan Not Available
NaphthoquinonesCaenorhabditis elegansExtended Lifespan Not Available
NaringeninDrosophila melanogasterExtended Lifespan Not Available
NaringeninCaenorhabditis elegansExtended Lifespan Not Available
NavitoclaxMus musculusExtended Lifespan Not Available
NavitoclaxHomo sapiens (cell culture) Extended Lifespan Not Available
N-benzyl hydroxylamine Homo sapiens (cell culture) Extended Lifespan Not Available
NebivololMus musculusExtended Lifespan Not Available
NectarineDrosophila melanogasterExtended Lifespan Not Available
Nicardipine hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
NicotinamideCaenorhabditis elegansExtended Lifespan Not Available
Nicotinamide adenine dinucleotideCaenorhabditis elegansExtended Lifespan Not Available
Nicotinamide mononucleotideMus musculusExtended Lifespan Not Available
Nicotinamide Saccharomyces cerevisiae Shortened Lifespan Not Available
NitrendipineCaenorhabditis elegansExtended Lifespan Not Available
N-methyl hydroxylamine Homo sapiens (cell culture) Extended Lifespan Not Available
N-nitrosodimethylamineCaenorhabditis elegansExtended Lifespan Not Available
Nolinospiroside FSaccharomyces cerevisiaeExtended Lifespan Not Available
Nordihydroguaiaretic acidMus musculusExtended Lifespan Not Available
Nordihydroguaiaretic acidAedes aegyptiExtended Lifespan Not Available
Nordihydroguaiaretic acidDrosophila melanogasterExtended Lifespan Not Available
Nortriptyline hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
N-t-butyl hydroxylamine Homo sapiens (cell culture) Extended Lifespan Not Available
N-tert-butyl-alpha-phenylnitroneMus musculusExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
Octoclothepin maleateCaenorhabditis elegansExtended Lifespan Not Available
Oleic AcidCaenorhabditis elegansExtended Lifespan Not Available
Olive OilRattus norvegicusExtended Lifespan Not Available
Omega-3 Monoacylglyceride Docosahexaenoic acidDrosophila melanogasterExtended Lifespan Not Available
Omega-6Caenorhabditis elegansExtended Lifespan Not Available
OrnithineCaenorhabditis elegansExtended Lifespan Not Available
Otophylloside BCaenorhabditis elegansExtended Lifespan Not Available
OxaloacetateCaenorhabditis elegansExtended Lifespan Not Available
OxaloacetateMus musculusExtended Lifespan Not Available
OxatomideCaenorhabditis elegansExtended Lifespan Not Available
OxolineCaenorhabditis elegansExtended Lifespan Not Available
OxyresveratrolCaenorhabditis elegansExtended Lifespan Not Available
OuabainDrosophila melanogasterExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
Panax notoginseng main root polysaccharideCaenorhabditis elegansExtended Lifespan Not Available
ParaquatCaenorhabditis elegansExtended Lifespan Not Available
PD-98059Drosophila melanogasterExtended Lifespan Not Available
Pergolide methanesulfonateCaenorhabditis elegansExtended Lifespan Not Available
PhenforminMus musculusExtended Lifespan Not Available
PhenforminCaenorhabditis elegansExtended Lifespan Not Available
PhosphoenolpyruvateCaenorhabditis elegansExtended Lifespan Not Available
Picolinic acidCaenorhabditis elegansExtended Lifespan Not Available
Piericidin ACaenorhabditis elegansExtended Lifespan Not Available
PinitolDrosophila melanogasterExtended Lifespan Not Available
Platinum nanoparticlesCaenorhabditis elegansExtended Lifespan Not Available
PlumbaginCaenorhabditis elegansExtended Lifespan Not Available
PolydatinCaenorhabditis elegansExtended Lifespan Not Available
PolyphenolsMus musculusExtended Lifespan Not Available
Pomegrenate juiceDrosophila melanogasterExtended Lifespan Not Available
PP2 AG1879Drosophila melanogasterExtended Lifespan Not Available
PregnenoloneCaenorhabditis elegansExtended Lifespan Not Available
ProanthocycanidinCaenorhabditis elegansExtended Lifespan Not Available
ProcyanidinsCaenorhabditis elegansExtended Lifespan Not Available
ProlineCaenorhabditis elegansExtended Lifespan Not Available
Promethazine hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
Propionylpromazine hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
Propyl gallateZaprionus paravittigerExtended Lifespan Not Available
Propyl gallateCaenorhabditis elegansExtended Lifespan Not Available
Protease treated royal jellyCaenorhabditis elegansExtended Lifespan Not Available
Protocatechuic acidCaenorhabditis elegansExtended Lifespan Not Available
Psora-4Caenorhabditis elegansExtended Lifespan Not Available
PutrescineCaenorhabditis elegansExtended Lifespan Not Available
Pyrrolidine dithiocarbamateDrosophila melanogasterExtended Lifespan Not Available
Phenylbutyric acidDrosophila melanogasterExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
QuercetinDrosophila melanogasterExtended Lifespan Not Available
QuercetinCaenorhabditis elegansExtended Lifespan Not Available
QuercetinHomo sapiens (cell culture) Extended Lifespan view
QuercetinMus musculusExtended Lifespan /Healthspanview
Q3GCaenorhabditis elegansExtended Lifespan Not Available
Q3MCaenorhabditis elegansExtended Lifespan Not Available
Quinidine sulfateCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
RapamycinMus musculusExtended Lifespan Not Available
RapamycinDrosophila melanogasterExtended Lifespan Not Available
RapamycinCaenorhabditis elegansExtended Lifespan Not Available
RasayanaDrosophila melanogasterExtended Lifespan Not Available
Reishi polysaccharideCaenorhabditis elegansExtended Lifespan Not Available
ReserpineCaenorhabditis elegansExtended Lifespan Not Available
ResveratrolNothobranchius furzeriExtended Lifespan Not Available
ResveratrolCaenorhabditis elegansExtended Lifespan Not Available
ResveratrolNothobranchius guentheriExtended Lifespan Not Available
ResveratrolAnastrepha ludensExtended Lifespan Not Available
ResveratrolSaccharomyces cerevisiaeExtended Lifespan Not Available
ResveratrolDrosophila melanogasterExtended Lifespan Not Available
ResveratrolApis melliferaExtended Lifespan Not Available
Retinoic acidHomo sapiens (cell culture) Extended Lifespan Not Available
Rhodiola roseaDrosophila melanogasterExtended Lifespan Not Available
Rhodiola roseaBombyx moriExtended Lifespan Not Available
RiboseCaenorhabditis elegansExtended Lifespan Not Available
RifampicinCaenorhabditis elegansExtended Lifespan Not Available
Rifamycin SVCaenorhabditis elegansExtended Lifespan Not Available
Rosmarinic acidCaenorhabditis elegansExtended Lifespan Not Available
RotenoneCaenorhabditis elegansExtended Lifespan Not Available
Royal JellyMus musculusExtended Lifespan Not Available
RoyalactinCaenorhabditis elegansExtended Lifespan Not Available
RutinCaenorhabditis elegansExtended Lifespan Not Available
RutinDrosophila melanogasterExtended Lifespan Not Available
RutinMus musculusExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
S,S-trolox-carnosineDrosophila melanogasterExtended Lifespan Not Available
S-allylmercaptocysteineCaenorhabditis elegansExtended Lifespan Not Available
S-allylcysteineCaenorhabditis elegansExtended Lifespan Not Available
SabutoclaxHomo sapiens (cell culture) Extended Lifespan Not Available
SalicylamineCaenorhabditis elegansExtended Lifespan /HealthspanNot Available
Salicylic acidCaenorhabditis elegansExtended Lifespan Not Available
SB203580Drosophila melanogasterExtended Lifespan Not Available
SelenocysteineCaenorhabditis elegansExtended Lifespan Not Available
SerineCaenorhabditis elegansExtended Lifespan Not Available
SesameDrosophila melanogasterExtended Lifespan Not Available
SesaminCaenorhabditis elegansExtended Lifespan Not Available
SevelamerDrosophila melanogasterExtended Lifespan Not Available
SimvastatinDrosophila melanogasterExtended Lifespan Not Available
SkQ1Drosophila melanogasterExtended Lifespan Not Available
SkQ1Ceriodaphnia affinisExtended Lifespan Not Available
SkQ1Podospora anserinaExtended Lifespan Not Available
Sodium borateDrosophila melanogasterShortened LifespanNot Available
Sodium butyrateDrosophila melanogasterExtended Lifespan Not Available
Sodium citrateMytilina brevispina var redunca Extended Lifespan Not Available
Sodium cyanideSaccharomyces cerevisiae (chronological) Extended Lifespan Not Available
Sodium hypophosphiteZaprionus paravittigerExtended Lifespan Not Available
Sodium pyruvateCaenorhabditis elegansExtended Lifespan Not Available
Sodium salicylate Rattus norvegicus(cell culture)Extended Lifespan Not Available
Sodium seleniteZaprionus paravittiger Extended Lifespan Not Available
Sodium tartrateMytilina brevispina var redunca Extended Lifespan Not Available
SorbitolSaccharomyces cerevisiaeExtended Lifespan Not Available
SP600125Drosophila melanogasterExtended Lifespan Not Available
SpeciosideCaenorhabditis elegansExtended Lifespan Not Available
SpermidineDrosophila melanogasterExtended Lifespan Not Available
SpermidineSaccharomyces cerevisiaeExtended Lifespan Not Available
SpermidineCaenorhabditis elegansExtended Lifespan Not Available
SpermineMus musculusExtended Lifespan Not Available
SQDBCaenorhabditis elegansExtended Lifespan Not Available
SRT1720Mus musculusExtended Lifespan Not Available
StaurosporineDrosophila melanogasterExtended Lifespan Not Available
SU 4312Caenorhabditis elegansExtended Lifespan Not Available
Suberoylanilide hydroxamic acidMus musculusExtended Lifespan Not Available
SuccinateCaenorhabditis elegansExtended Lifespan Not Available
SulfamethoxazoleCaenorhabditis elegansExtended Lifespan Not Available
Sulforaphane Caenorhabditis elegansExtended Lifespan Not Available
Sulforaphane Homo sapiens (cell culture) Extended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
TamarixetinCaenorhabditis elegans Extended Lifespan Not Available
Tannic acidCaenorhabditis elegansExtended Lifespan Not Available
TartrateMytilina brevispinaExtended Lifespan Not Available
TaurineDrosophila melanogasterShortened LifespanNot Available
TaurineCaenorhabditis elegansExtended Lifespan Not Available
TaxifolinCaenorhabditis elegansExtended Lifespan Not Available
TetrahydrocurcuminMus musculusExtended Lifespan Not Available
Thiazolidine carboxylic acidDrosophila melanogasterExtended Lifespan Not Available
Thioflavin TCaenorhabditis elegansExtended Lifespan Not Available
Thioridazine hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
ThreonineCaenorhabditis elegansExtended Lifespan Not Available
ThyroxineRattus norvegicus Extended Lifespan Not Available
TocotrienolCaenorhabditis elegansExtended Lifespan Not Available
Torin 1Drosophila melanogasterExtended Lifespan Not Available
TrametinibDrosophila melanogasterExtended Lifespan Not Available
TrehaloseCaenorhabditis elegansExtended Lifespan Not Available
Trequinsin hydrochlorideCaenorhabditis elegansExtended Lifespan Not Available
Trichostatin ADrosophila melanogasterExtended Lifespan Not Available
TrimethadioneCaenorhabditis elegansExtended Lifespan Not Available
TroloxCaenorhabditis elegansExtended Lifespan Not Available
TryptophanCaenorhabditis elegansExtended Lifespan Not Available
Turmeric powderDrosophila melanogasterExtended Lifespan Not Available
TyrosineCaenorhabditis elegansExtended Lifespan Not Available
TyrosolCaenorhabditis elegansExtended Lifespan Not Available
Tyrphostin 1Drosophila melanogasterExtended Lifespan Not Available
Tyrphostin 9Drosophila melanogasterExtended Lifespan Not Available
Tyrphostin AG 1295Drosophila melanogasterExtended Lifespan Not Available
Tyrphostin AG 1478Drosophila melanogasterExtended Lifespan Not Available
Tyrphostin AG 1478Caenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
Urolithin ACaenorhabditis elegansLifespan extension Not Available
Urolithin BCaenorhabditis elegansLifespan extension Not Available
Urolithin CCaenorhabditis elegansLifespan extension Not Available
Urolithin DCaenorhabditis elegansLifespan extension Not Available
Ursolic acidCaenorhabditis elegansLifespan extension Not Available
Ursolic acidDrosophila melanogasterLifespan extension Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
ValineCaenorhabditis elegansExtended Lifespan Not Available
Valproic acidCaenorhabditis elegansExtended Lifespan Not Available
VerminosideCaenorhabditis elegansExtended Lifespan Not Available
VI-28Mus musculusExtended Lifespan Not Available
VinpocetineCaenorhabditis elegansExtended Lifespan Not Available
Vitamin CMus musculusExtended Lifespan /Healthspanview
Vitamin CParamecium tetraureliaExtended Lifespan Not Available
Vitamin CCaenorhabditis elegansShortened LifespanNot Available
Vitamin CHomo sapiens(cell culture)Extended Lifespan view
Vitamin D3Caenorhabditis elegansExtended Lifespan Not Available
Vitamin E Asplanchna brightwelli Extended Lifespan Not Available
Vitamin E Zaprionus paravittiger Extended Lifespan Not Available
Vitamin E Philodina acuticornis Extended Lifespan Not Available
Vitamin E Caenorhabditis elegans Extended Lifespan Not Available
VitexinCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
WortmanninDrosophila melanogasterExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
XyloseCaenorhabditis elegansExtended Lifespan Not Available
Compounds NameOrganismAging PhenotypeRNA-seq
2-mercaptoethanol Mus musculus Extended Lifespan Not Available
2-mercaptoethylamine hydrochloride Mus musculus Extended Lifespan Not Available
2-deoxyglucoseHomo sapiens (cell culture) Extended Lifespan Not Available
2-deoxyglucoseMus musculus Extended HealthspanNot Available
17-DMAGMus musculus Extended Lifespan Not Available
17α-oestradiolMus musculus Extended Lifespan Not Available

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