| ENSCAFG00000016714 |
GO:0044212 |
transcription regulatory region DNA binding |
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0000981 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0000990 |
transcription factor activity, core RNA polymerase binding |
Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0001046 |
core promoter sequence-specific DNA binding |
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0001085 |
RNA polymerase II transcription factor binding |
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0001228 |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding |
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0002020 |
protease binding |
Interacting selectively and non-covalently with any protease or peptidase. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0002039 |
p53 binding |
Interacting selectively and non-covalently with one of the p53 family of proteins. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0003682 |
chromatin binding |
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0003730 |
mRNA 3'-UTR binding |
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule. |
IEA |
molecular_function |
| ENSCAFG00000016714 |
GO:0005507 |
copper ion binding |
Interacting selectively and non-covalently with copper (Cu) ions. |
IEA |
molecular_function |