The detail information of Ataxia, cerebellar, neonatal, GRM1-related
OMIA Basic Information
Possible human homologues (MIM numbers):
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Recessive
Considered a defect: yes
Year key mutation first reported: 2011
Species-specific name: Bandera's neonatal ataxia
Species-specific symbol: BNAt
More detail information can see in
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | History | Breed Source |
|---|---|---|---|---|---|---|
| CB80 | Coton de Tulear | 25.4-27.9 cm (male), 22.9-25.4 cm (female) | 4.1-6.8 kg (male), 3.6-5.9 kg (female) | Madagascar |
Associated Gene
| Symbol | Description | Species | Position | Other Links |
|---|---|---|---|---|
| GRM1 | glutamate receptor, metabotropic 1 | Canis lupus familiaris | Chr1 : 37381684 - 37767160 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2011 |
Zeng,R.,Farias,FH.,Johnson,GS.,McKay,SD.,Schnabel,RD.,Decker,JE.,Taylor,JF.,Mann,CS.,Katz,ML.,Johnson,GC.,Coates,JR.,O'Brien,DP.: :
A truncated retrotransposon disrupts the GRM1 coding sequence in Coton de Tulear dogs with Bandera's neonatal ataxia. J Vet Intern Med 25:267-72, 2011. Pubmed reference: 21281350 . DOI: 10.1111/j.1939-1676.2010.0666.x . |
| 2002 |
Coates,J.R.,O'Brien,D.P.,Kline,K.L.,Storts,R.W.,Johnson,G.C.,Shelton,G.D.,Patterson,E.E.,Abbott,L.C.: :
Neonatal cerebellar ataxia in Coton de Tulear dogs Journal of Veterinary Internal Medicine 16:680-9, 2002. Pubmed reference: 12465765 . |