The detail information of Golden Retriever PRA 1
OMIA Basic Information
Possible human homologues (MIM numbers): -
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Recessive
Considered a defect: yes
Year key mutation first reported: 2011
Species-specific name: -
Species-specific symbol: GR_PRA1
More detail information can see in
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | History | Breed Source |
|---|---|---|---|---|---|---|
| CB116 | Golden Retriever | 58.4-61 cm (male), 54.6-57.2 cm (female) | 29.5-34 kg (male), 24.9-29.5 kg (female) | United Kingdom (Scotland) |
Associated Gene
| Symbol | Description | Species | Position | Other Links |
|---|---|---|---|---|
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | Canis lupus familiaris | Chr37 : 26151769 - 26167414 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2012 |
Miyadera,K.,Acland,G.M.,Aguirre,G.D.: :
Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome 23:40-61, 2012. Pubmed reference: 22065099 . DOI: 10.1007/s00335-011-9361-3 . |
| 2011 |
Downs,L.M.,Wallin-Håkansson,B.,Boursnell,M.,Marklund,S.,Hedhammar,Å.,Truvé,K.,Hübinette,L.,Lindblad-Toh,K.,Bergström,T.,Mellersh,C.S.: :
A frameshift mutation in golden retriever dogs with progressive retinal atrophy endorses SLC4A3 as a candidate gene for human retinal degenerations. PLoS One 6:e21452, 2011. Pubmed reference: 21738669 . DOI: 10.1371/journal.pone.0021452 . |