The detail information of Chronic valvular disease
OMIA Basic Information
Possible human homologues (MIM numbers): -
Mendelian trait/disorder: unknown
Mode of inheritance: -
Considered a defect: yes
Year key mutation first reported: -
Species-specific name: -
Species-specific symbol: -
More detail information can see in
Associated Breeds
There are associated breeds.
Associated Gene
Symbol | Description | Species | Position | Other Links |
---|---|---|---|---|
THRB | thyroid hormone receptor, beta | Canis lupus familiaris | Chr23 : 19582486 - 19954456 | Homologene, Ensembl, NCBI gene |
THR | thyroid hormone receptor beta1 | - | Chr- : - - - | Homologene, Ensembl, NCBI gene |
THRA | thyroid hormone receptor, alpha | Canis lupus familiaris | Chr9 : 23286090 - 23262655 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2000 |
Karlstam,E.,Haggstrom,J.,Kvart,C.,Jonsson,L.,Michaelsson,M.: :
Pulmonary artery lesions in cavalier King Charles spaniels Veterinary Record 147:166-167, 2000. Pubmed reference: 10975336 . |
1999 |
Shahrara,S.,Tidholm,A.,Drvota,V.,Haggstom,J.,Sylven,C.: :
Upregulation of thyroid hormone receptor beta(1) and beta(2) messenger RNA in the myocardium of dogs with dilated cardiomyopathy or chronic valvular disease American Journal of Veterinary Research 60:848-852, 1999. Pubmed reference: 10407478 . |
1996 |
Swenson,L.,Haggstrom,J.,Kvart,C.,Juneja,R.K.: :
Relationship between parental cardiac status in Cavalier King Charles spaniels and prevalence and severity of chronic valvular disease in offspring Journal of the American Veterinary Medical Association 208:2009 ff., 1996. |