Disease Description: This familial disease is characterized by reduced cortisol effects, due to a GC receptor (GR) defect, which is compensated by hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis.

Inherit Mode: autosomal recessive

Disease Symptom: As a consequence, patients present with signs of adrenal overproduction of mineralocorticoids (hypertension and hypokalaemic alkalosis) and, in females, of androgens (hirsutism, male pattern of baldness, menstrual irregularities).

Disease Cause: -

Disease Diagnose: -

Treat Method: -

Breeder Advice: -

Disease Description Source: Link