The detail information of Coloboma
Basic Information

Disease Description: An abnormal development of the eye, usually seen in collies, which can lead to blindness

Inherit Mode: -

Disease Symptom: As an inherited disorder, it represents part of Collie Eye Anomaly disorder, but also occurs sporadically as non-inherited birth defect. In both cases, the size of the defect varies from dog to dog. The deformity is non-progressive and can be found in one or both eyes. If the defect is large, vision will be compromised.

Disease Cause: -

Disease Diagnose: -

Treat Method: There is no effective treatment

Breeder Advice: It is best to avoid breeding affected dogs.

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Coloboma - Autosomal Recessive -
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB5 Alaskan Malamute Affectionate, loyal, playful but dignified 63.5 cm (male), 58.4 cm (female) 38.6 kg (male), 34 kg (female) United States
CB21 Basset Fauve de Bretagne(Fawn Brittany Basset) Smart, Cheerful, Determined 32–38 cm (13–15 in) France
CB89 Dogo Argentino Loyal, trustworthy,courageous 61-68.6 cm (male), 59.7-66 cm (female) 36.3-45.4 kg Argentina
CB98 English Toy Spaniel Affectionate, Alert, Merry 22.9-25.4 cm 3.6-6.4 kg England
CB111 German Short-Haired Pointer Friendly, smart, willing to please 58.4-63.5 cm (male), 53.3-58.4 cm (female) 24.9-31.8 kg (male), 20.4-27.2 kg (female) Germany
CB117 Gordon Setter Bold, confident, and resolute afield; sweetly affectionate by the fireside 61-68.6 cm (male), 58.4-66 cm (female) 24.9-36.3 kg (male), 20.4-31.8 kg (female) United Kingdom (Scotland)
CB148 Lagotto Romagnolo(Romagna Water Dog) Easygoing, affectionate, and eager to please 43.2-48.3 cm (male), 40.6-45.7 cm (female) 12.9-15.9 kg (male), 10.9-14.1 kg (female) Italy
CB217 Japanese Shiba Inu Alert, active, and attentive 35.6-43.2 cm (male), 33-40.6 cm (female) 8.2-10.9 kg (male), 6.8-9.1 kg (female) Japan
References
1981 Gelatt,K.N.,Powell,G.,Huston,K.: :
Inheritance of microphthalmia with coloboma in the Australian Sheep dog. American Journal of Veterinary Research 42:1686-1690, 1981.
Pubmed reference: 7325429 .
1973 Gelatt,K.N.,McGill,L.D.: :
Clinical characteristics of microphthalmia with colobomas of the Australian Shepherd dog Journal of the American Veterinary Medical Association 162:393-396, 1973.
Pubmed reference: 4691375 .