Disease name | Psoriasis |
---|---|
Classfication | Skin disease |
Related Enzyme(s) | |
EFO | EFO:0000676 |
DOID | 8893 |
OMIM | |
NCI | |
Definition |
Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
---|---|---|---|---|---|---|---|---|
FLNA | Human | ADAR1;ADAR2 | 1 | NA | Decreased editing in highly conserved recoding sites in FLNA, might alter their function, leading to keratinocyte prolifera- tion, and impaired differentiation. And the decreased A-to-I ed- iting in keratinocytes could be involved in the exacerbation of psoriasis. |