EDK
Editome Disease Knowledgebase
Astrocytomas
| Disease name | Astrocytomas |
|---|---|
| Classfication | Cancer |
| Related Enzyme(s) | |
| EFO | EFO:0000272 |
| DOID | - |
| OMIM | |
| NCI | |
| Definition | Astrocytomas are a type of cancer of the brain. They originate in a particular kind of glial cells, star-shaped brain cells in the cerebrum called astrocytes. This type of tumor does not usually spread outside the brain and spinal cord and it does not usually affect other organs. Astrocytomas are the most common glioma and can occur in most parts of the brain and occasionally in the spinal cord. |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| CDC14B | Human | ADAR2 | 13 | A-to-I | CDC14B editing and expression are progressively impaired in astrocytomas from grade I to IV, being very low in GBMs. |