URL: | http://bioinfo.icgeb.res.in/kipho |
Full name: | malaria parasite kinome and phosphatome portal |
Description: | The aim of this work is to provide researcher community a resource that can be easily queried to obtain information related to structure, function and literature about Plasmodium kinase/phosphatase. Most of the information is dynamically retrieved from publicly available repositories which are integrated with our curated data in our internal database. |
Year founded: | 2017 |
Last update: | 2017 |
Version: | |
Accessibility: | |
Country/Region: | India |
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Data object: |
NA
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University/Institution: | International Centre for Genetic Engineering and Biotechnology |
Address: | Translational Bioinformatics Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India |
City: | New Delhi |
Province/State: | |
Country/Region: | India |
Contact name (PI/Team): | Dinesh Gupta |
Contact email (PI/Helpdesk): | dinesh@icgeb.res.in |
KiPho: malaria parasite kinome and phosphatome portal. [PMID: 29220464]
The Plasmodium kinases and phosphatases play an essential role in the regulation of substrate reversible-phosphorylation and overall cellular homeostasis. Reversible phosphorylation is one of the key post-translational modifications (PTMs) essential for parasite survival. Thus, a complete and comprehensive information of malarial kinases and phosphatases as a single web resource will not only aid in systematic and better understanding of the PTMs, but also facilitate efforts to look for novel drug targets for malaria. In the current work, we have developed KiPho, a comprehensive and one step web-based information resource for Plasmodium kinases and phosphatases. To develop KiPho, we have made use of search methods to retrieve, consolidate and integrate predicted as well as annotated information from several publically available web repositories. Additionally, we have incorporated relevant and manually curated data, which will be updated from time to time with the availability of new information. The KiPho (Malaria Parasite Kinome-Phosphatome) resource is freely available at http://bioinfo.icgeb.res.in/kipho. |