| URL: | http://bioinfo.imtech.res.in/manojk/zikavr |
| Full name: | Manoj Kumar |
| Description: | Zika virus (ZIKV) is a flavivirus belonging to family Flaviviridae and is one of the major factors for current outbreak spreading over several areas of Africa, Southeast Asia, and in pacific islands. Zika infection was declared an emergency epidemic threat worldwide by World Health Organization (WHO) in early 2016. |
| Year founded: | 2016 |
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| Country/Region: | India |
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| University/Institution: | Institute of Microbial Technology |
| Address: | Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific and Industrial Research (CSIR), Sector 39A, Chandigarh, 160036, India. |
| City: | Chandigarh |
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| Country/Region: | India |
| Contact name (PI/Team): | Manoj Kumar |
| Contact email (PI/Helpdesk): | manojk@imtech.res.in |
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ZikaVR: An Integrated Zika Virus Resource for Genomics, Proteomics, Phylogenetic and Therapeutic Analysis. [PMID: 27633273]
Current Zika virus (ZIKV) outbreaks that spread in several areas of Africa, Southeast Asia, and in pacific islands is declared as a global health emergency by World Health Organization (WHO). It causes Zika fever and illness ranging from severe autoimmune to neurological complications in humans. To facilitate research on this virus, we have developed an integrative multi-omics platform; ZikaVR (http://bioinfo.imtech.res.in/manojk/zikavr/), dedicated to the ZIKV genomic, proteomic and therapeutic knowledge. It comprises of whole genome sequences, their respective functional information regarding proteins, genes, and structural content. Additionally, it also delivers sophisticated analysis such as whole-genome alignments, conservation and variation, , codon context, usage bias and phylogenetic inferences at whole genome and proteome level with user-friendly visual environment. Further, glycosylation sites and molecular diagnostic primers were also analyzed. Most importantly, we also proposed potential therapeutically imperative constituents namely vaccine epitopes, siRNAs, miRNAs, sgRNAs and repurposing drug candidates. |