BIG Search is a scalable text search engine built based on ElasticSearch (a highly scalable open-source
full-text search and analytics engine based on Apache Lucene). It features cross-domain search and facilitates
users to gain access to a wide range of biomedical data, not only from BIGD databases but also partner databases
throughout the world.
Title: Prevalence and spectrum of AKT1, PIK3CA, PTEN and TP53 somatic mutations in Chinese breast cancer patients
Description: Breast cancer is the leading cause of cancer-related death among women. AKT1, PIK3CA, PTEN and TP53 mutations were common observed in breast cancer representing potential clinical biomarkers for breast cancer classification and treatment. In this study, the complete coding regions and exon-intron boundaries of AKT1, PIK3CA, PTEN and TP53 genes were sequenced and analyzed in breast tumor from 313 Chinese breast cancer patients using microfluidic PCR-based target enrichment and next-generation sequencing technology.
BasicInfo : PRJCA000999; Targeted Locus (Loci) Raw sequence reads; Medical