BIG Search

e.g., PRJCA000126;SAMC000385;tp53;EGFR; human; KaKs_Calculator; GenBank; Zhang;

All databases: 7623428

BioProject: PRJCA000453 Information

  • Accession: PRJCA000453
  • Title: PRJCA000453 Information
  • Description: Exome chip data of human ESCC cases and controls
  • BasicInfo : PRJCA000453; Exome chip; Variation; Medical

BioProject: PRJCA000125 Information

  • Accession: PRJCA000125
  • Title: PRJCA000125 Information
  • Description: Tree Shrew Glioblastoma Model Recapitulates Features of Human Glioblastoma
  • Samples: SAMC000383
  • GSAs: CRA000021
  • BasicInfo : PRJCA000125; RNA-seq of tree shrew tumors; Transcriptome or Gene expression; Model organism

BioProject: PRJCA000229 Information

BioProject: PRJCA000248 Information

  • Accession: PRJCA000248
  • Title: PRJCA000248 Information
  • Description: We performed whole genome bisulfite sequencing (WGBS) for 57 blastocysts and 29 trophectoderm samples with different morphological grades during assisted reproductive technology(ART) practices.
  • Samples: SAMC018834 SAMC017372 SAMC017371 SAMC017370 SAMC017369 SAMC017368 more
  • GSAs: CRA000114
  • BasicInfo : PRJCA000248; Human Blastocyst Methylome; Epigenomics; Medical

BioProject: PRJCA000273 Information

  • Accession: PRJCA000273
  • Title: PRJCA000273 Information
  • Description: PAR-CLIP sequencing for YTHDF1 and YTHDF3 in human HeLa cells
  • Samples: SAMC007190 SAMC007189
  • GSAs: CRA000133
  • BasicInfo : PRJCA000273; PAR-CLIP-seq of m6A readers; Transcriptome or Gene expression; Model organism

BioProject: PRJCA000484 Information

  • Accession: PRJCA000484
  • Title: PRJCA000484 Information
  • Description: chromatin accessibility landscape by characterizing DNase I hypersensitive sites (DHSs) in human embryos
  • Samples: SAMC017364 SAMC017363 SAMC017362 SAMC017361 SAMC017360 SAMC017359 more
  • GSAs: CRA000297
  • BasicInfo : PRJCA000484; The Establishment of Chromatin Accessibility Landscape during Human Early Embryogenesis; Whole genome sequencing Epigenomics Raw sequence reads; Model organism

BioProject: PRJCA000216 Information

  • Accession: PRJCA000216
  • Title: PRJCA000216 Information
  • Description: Sequenced mitochondrial genome for different tissue of human in order to find the hetero genotype
  • Samples: SAMC004504
  • GSAs: CRA000090
  • BasicInfo : PRJCA000216; Human mitochondrial genome sequence project; Whole genome sequencing; Medical

BioProject: PRJCA000315 Information

  • Accession: PRJCA000315
  • Title: PRJCA000315 Information
  • Description: By m5C sequencing in human HeLa cells and mouse tissues, we aimed to uncover RNA distributive features in whole mRNA transcriptomes and its tissue-specific and dynamic features across mammalian transcriptomes.
  • Samples: SAMC007659 SAMC007658 SAMC007657 SAMC007656 SAMC007655 SAMC007654 more
  • GSAs: CRA000162
  • BasicInfo : PRJCA000315; RNA m5C sequencing in human HeLa cells and mouse tissues; Epigenomics; Model organism

BioProject: PRJCA000775 Information

  • Accession: PRJCA000775
  • Title: PRJCA000775 Information
  • Description: This project aims to study human memory capacity, including short-term memory and long-term memory, systematically via genome-wide association studies
  • BasicInfo : PRJCA000775; Genome-wide association study of human memory performance; Phenotype or Genotype; Medical

BioProject: PRJCA000384 Information

  • Accession: PRJCA000384
  • Title: PRJCA000384 Information
  • Description: Megakaryocytes (MKs) in adult marrow produce platelets that play important roles in blood coagulation and hemostasis. Mono-allelic mutations of the master transcription factor RUNX1 lead to familial platelet disorder (FPD) characterized by defective MK and platelet development. However, the molecular mechanisms in FPD remain unclear. Previously, we generated human induced pluripotent stem cells (iPSCs) from FPD patients containing a RUNX1 nonsense mutation: Indeed MKs developed from FPD-iPSCs was reduced and targeted correction of the RUNX1 mutation restored MK production. In this study, we took advantage of isogenic pairs of FPD-iPSCs and MK differentiation system to identify RUNX1 direct target genes. Using integrative genomic and bioinformatic analysis of hematopoietic progenitor cells generated from FPD iPSCs and mutation-corrected isogenic control, we identified two gene sets whose transcription are either up- or down-regulated by RUNX1 binding in mutation-corrected and normal iPSCs.
  • Samples: SAMC012473 SAMC012472 SAMC012471 SAMC012470 SAMC012469
  • GSAs: CRA000215
  • BasicInfo : PRJCA000384; Human NOTCH4 Is a Key Target of RUNX1 in Megakaryocytic Differentiation; Epigenomics; Medical