National Genomics Data Center

BIG Search

BIG Search is a scalable text search engine built based on ElasticSearch (a highly scalable open-source full-text search and analytics engine based on Apache Lucene). It features cross-domain search and facilitates users to gain access to a wide range of biomedical data, not only from BIGD databases but also partner databases throughout the world.

e.g., PRJCA000126;SAMC000385;tp53;EGFR; human; KaKs_Calculator; GenBank

Total 11 record(s) from 2019nCoVR Literature

Publication: Analysis of early renal injury in COVID-19 and diagnostic value of multi-index combined detection
abst: filtration rate (eGFR), endogenous creatinine clearance (Ccr) and urine microalbumin / urinary, blood urea nitrogen (BUN), the abnormal rates of eGFR, Ccr, and UACR were 66.7%, 41.7%, and 41.7
basicInfo: filtration rate (eGFR), endogenous creatinine clearance (Ccr) and urine microalbumin / urinary, blood urea nitrogen (BUN), the abnormal rates of eGFR, Ccr, and UACR were 66.7%, 41.7%, and 41.7
Publication: Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)-Associated Interstitial Lung Disease During the COVID-19 Pandemic.
title: Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)-Associated Interstitial Lung Disease During the COVID-19 Pandemic.
title: Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)-Associated Interstitial Lung Disease During the COVID-19 Pandemic.
keyword: COVID-19,EGFR TKI,ILD
Publication: Inhibition of herpes simplex virus by myricetin through targeting viral gD protein and cellular EGFR/PI3K/Akt pathway.
abst: as acyclovir. Myricetin also down-regulate the cellular EGFR/PI3K/Akt signaling pathway to further, agent targeting both virus gD protein and cellular EGFR/PI3K/Akt pathway.
title: Inhibition of herpes simplex virus by myricetin through targeting viral gD protein and cellular EGFR/PI3K/Akt pathway.
title: Inhibition of herpes simplex virus by myricetin through targeting viral gD protein and cellular EGFR/PI3K/Akt pathway.
basicInfo: as acyclovir. Myricetin also down-regulate the cellular EGFR/PI3K/Akt signaling pathway to further, agent targeting both virus gD protein and cellular EGFR/PI3K/Akt pathway.
keyword: Membrane fusion,Myricetin,Virus Adsorption,Anti-hsv,Egfr/pi3k/akt Pathway
Publication: A phase I/II study of poziotinib combined with paclitaxel and trastuzumab in patients with HER2-positive advanced gastric cancer.
abst: targets EGFR, HER2, and HER4. This prospective, multicenter, open-label, phase I/II study determined the
basicInfo: targets EGFR, HER2, and HER4. This prospective, multicenter, open-label, phase I/II study determined the
Publication: Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases.
keyword: , Cyclooxygenase-2,Egfr, Epidermal Growth Factor Receptor,Mmp, Matrix Metalloproteinase,Vegf, Vascular
Publication: Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
abst: a retrospective analysis of estimated glomerular filtration rate (eGFR) along with other clinical
basicInfo: a retrospective analysis of estimated glomerular filtration rate (eGFR) along with other clinical
Publication: Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients.
abst: patients (all p < 0.05), while eGFR decreased (p < 0.001). Monocyte-lymphocyte ratio (MLR) was
basicInfo: patients (all p < 0.05), while eGFR decreased (p < 0.001). Monocyte-lymphocyte ratio (MLR) was
Publication: A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia.
abst: eGFR 36.5 [23-47.5]) with SARS-CoV2 induced pneumonia. At admission, all had immunosuppression
basicInfo: eGFR 36.5 [23-47.5]) with SARS-CoV2 induced pneumonia. At admission, all had immunosuppression
Publication: Recurrence of SARS-CoV-2 PCR positivity in COVID-19 patients: a single center experience and potential implications
abst: hospitalization for cholinesterase, fibrinogen, albumin, prealbumin, calcium, eGFR, creatinine; highest levels of
basicInfo: hospitalization for cholinesterase, fibrinogen, albumin, prealbumin, calcium, eGFR, creatinine; highest levels of
Publication: Therapeutic targets and signaling mechanisms of vitamin C activity against sepsis: a bioinformatics study.
abst: . These core targets were epidermal growth factor receptor (EGFR), mitogen-activated protein kinase
basicInfo: . These core targets were epidermal growth factor receptor (EGFR), mitogen-activated protein kinase