Felis catus
Information about Cat Genome
Felis catus, the domestic cat, provides several valuable models for infectious disease, including a model for human AIDS. With a large number of recognized breeds, the cat is also a valuable resource for studying phenotypic diversity and evolution. The cat genome will further facilitate research in human medicine as some rare diseases that occur in humans also occur in this popular pet. The domestic cat diploid genome is organized in 18 pairs of autosomes and two sex chromosomes. The first genome sequence of domestic cat was published in 2007[1].
the update version (Felis_catus_9.0) was submitted by Genome Sequencing Center (GSC) at Washington University (WashU) School of Medicine on 2017, it has the following information:
● Genome Size: ~2.34Gb
● Number of Chromosomes: 19
● Number of Unplaced Scaffolds: 4,412
● Genome Size: ~2.34Gb
● Number of Chromosomes: 19
● Number of Unplaced Scaffolds: 4,412
Genome Re-sequencing Projects and Variation Identification
Recently, many of cat accessions have been re-sequenced, such as:
●Felis catus Raw sequence reads (SRA: SRP061392, 48 accessions).
●The genetics of kinked tail trait in Asian domestic cats (SRA: SRP073776, 13 accessions).
We gathered these data, and identified variations using our standard computational pipeline.
●Felis catus Raw sequence reads (SRA: SRP061392, 48 accessions).
●The genetics of kinked tail trait in Asian domestic cats (SRA: SRP073776, 13 accessions).
We gathered these data, and identified variations using our standard computational pipeline.
References
[1] Pontius JU1, Mullikin JC, Smith DR; Agencourt Sequencing Team, Lindblad-Toh K, Gnerre S, Clamp M, Chang J, Stephens R, Neelam B, Volfovsky N, Schäffer AA, Agarwala R, Narfström K, Murphy WJ, Giger U, Roca AL, Antunes A, Menotti-Raymond M, Yuhki N, Pecon-Slattery J, Johnson WE, Bourque G, Tesler G; NISC Comparative Sequencing Program, O'Brien SJ: Initial sequence and comparative analysis of the cat genome. Genome Res, 17(11):1675-89. [PMID=17975172]