DAC NO.: HDAC000872
DAC name: SMG1i synergize with XR-2
Contact person: Xiao Fei
URL: https://www.researchgate.net/scientific-contributions/Fei-Xiao-2055055980
Description: This study found that a novel NMD inhibitor, SMG1i could synergize with MDM2 inhibitor XR-2 in TP53 wild-type solid tumor models. The combination of these two agents could increase cell apoptosis, damage cell viability, arrest cell cycle synergistically.