Enzyme - EDK - BIG Data Center

Enzyme	Full Name	Location	Ensembl	Targets	Related Diseases	Aliases
ADAR1	Adenosine deaminase, RNA specific	Chr1:154582057..154631560	ENSG00000160710	AZIN1 FLNB NEIL1 GLI1 hsa-Let-7a-1 hsa-miR-222 hsa-miR-381	Aicardi-Goutires syndrome Breast Cancer Dyschromatosis Symmetrica Hereditaria Human immunodeficiency virus infectious disease Measles Vesicular stomatitis Anxiety disorder Chronic Myeloid Leukemia Lung Cancer Sepsis Melanoma Leukemia Esophageal Squamous Cell Carcinoma Epithelial Ovarian Cancers Ovarian Cancer Sepsis	AGS6 DRADA DSH DSRAD G1P1 IFI-4 IFI4 K88DSRBP P136
ADAR2	Adenosine deaminase, RNA specific B1	Chr21:45074578..45226563	ENSG00000197381	GRIA2 GRIK1 GRIK2 BLCAP hsa-miR-222	Astrocytomas Amyotrophic Lateral Sclerosis Epileptic Glaucoma Glioblastoma	ADARB1 DRABA2 DRADA2 RED1
ADAR3	Adenosine deaminase, RNA specific B2	Chr10:1177313..1737476	ENSG00000185736	GRIA2	Glioblastoma Astrocytomas	ADARB2 DRABA2 RED2
AID	Activation-induced cytidine deaminase	Chr12:8602166..8612970	ENSG00000111732	CDKN2A CDKN2B TP53 INK4A	Gastric Cancer Cholangiocarcinoma Chronic Hepatitis	AICDA ARP2 CDA2 HIGM2 HEL-S-284
APOBEC1	Apolipoprotein B mRNA editing enzyme catalytic subunit 1	Chr12:8602166..8612970	ENSG00000111701	apoB mRNA	Hepatocellular Carcinoma	BEDP HEPR CDAR1 APOBEC-1
APOBEC3	Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3	Chr22:38957522..39087743	ENSG00000128383 ENSG00000179750 ENSG00000244509 ENSG00000243811 ENSG00000128394 ENSG00000239713	virus HBV core protein, enhancer II, promoter	Acute Myeloid Leukemia Hepatocellular Carcinoma Chronic Hepatitis Renal Cell Carcinoma	APOBEC3A APOBEC3B APOBEC3C APOBEC3DE APOBEC3F APOBEC3G APOBEC3H

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