LymphTF-DB Edit

Citations: 6

z-index: 0.5

Basic information
Short name LymphTF-DB
Full name B and T Lymphocyte Transcription Factor Activity in Mouse
Description This website is designed as a portal of information regarding transcription factor (TF) activity in the developing B and T cells (lymphocytes) in the mouse.
URL http://www.iupui.edu/~tfinterx
Year founded
Last update & version
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Indiana University-Purdue University Indianapolis
Address
City Indianapolis
Province/State IN
Country/Region United States
Contact name (PI/Team) N B Perumal
Contact email (PI/Helpdesk) nperumal@iupui.edu
Data information
Data object
Data type
Database category
Major organism
Keyword
Publications
  • LymphTF-DB: a database of transcription factors involved in lymphocyte development. [PMID: 17361201]
    Childress PJ, Fletcher RL, Perumal NB.

    B and T cells develop following a similar early stepwise progression to later stages where multiple developmental options are available. These developmental regimes necessitate differential gene expression regulated by a large number of transcription factors (TFs). The resultant burgeoning amount of information has opened a knowledge gap between TF activities during lymphocyte development and a researcher's experiments. We have created the LymphTF database (DB) to fill this gap. This DB holds interactions between individual TFs and their specific targets at a given developmental time. By storing such interactions as a function of developmental progression, we hope to advance the elucidation of regulatory networks that guide lymphocyte development. Besides queries for TF-target gene interactions in developmental stages, the DB provides a graphical representation of downloadable target gene regulatory sequences with locations of the transcriptional start sites and TF-binding sites. The LymphTF-DB can be accessed freely on the web at http://www.iupui.edu/~tfinterx/.

    Genes Immun 2007:8(4)

    6 Citations (from Europe PMC, 2019-07-27)

Rank

  • Ranking in all databases: No. 3753
  • Ranking in category/categories:
    • Interaction: No. 545
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of LymphTF-DB.

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Record metadata

  • Created on: 2019-07-01
    • ***ina@***c.cn [2019-07-01]

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