circAtlas Edit

Citations: 0

z-index: 0

Basic information
Short name circAtlas
Full name
Description circAtlas 2.0 integrates millions of circRNAs across 7 species (human, macaca, mouse, rat, pig, chicken, dog) and a variety of tissues. The circAtlas 2.0 can fill this gap by integrating the most comprehensive circRNAs and their expression and functional profiles in vertebrates, which provides a foundation for circRNA studies and serves as a powerful starting point to investigate their biological significance.
URL http://circatlas.biols.ac.cn
Year founded 2018
Last update & version v2.0
Availability Free to academic users only
Contact information
University/Institution hosted Beijing Institutes of Life Science, Chinese Academy of Sciences
Address
City Beijing
Province/State
Country/Region China
Contact name (PI/Team) Fangqing Zhao
Contact email (PI/Helpdesk) zhfq@biols.ac.cn
Data information
Data object
Data type
Database category
Major organism
Keyword
Publications
  • Expanded Expression Landscape and Prioritization of Circular RNAs in Mammals. [PMID: 30893614]
    Ji P, Wu W, Chen S, Zheng Y, Zhou L, Zhang J, Cheng H, Yan J, Zhang S, Yang P, Zhao F.

    Circular RNAs (circRNAs) are emerging as essential regulators of various biological and disease processes. To comprehensively understand the diversity of circRNAs and prioritize their importance, we present a large-scale study of circRNA repertoires from multiple tissues from human, macaque, and mouse. We discovered totals of 104,388, 96,675, and 82,321 circRNAs from the three species, respectively, with an average of 72.6% being successfully assembled into full-length transcripts for each species. Using these full-length circRNAs, we identified thousands of evolutionarily conserved circRNAs that were valuable for functional screening and prioritization. By constructing both species-specific and conserved gene co-expression networks, we inferred circRNA functions on a global scale and prioritized promising functional candidates. To illustrate how well-established prior knowledge facilitates to screen functional candidates, we used the circRNA co-expression networks to prioritize circRNAs that may be involved in liver tumorigenesis and experimentally validated their functions.

    Cell Rep 2019:26(12)

    0 Citations (from Europe PMC, 2019-04-13)

Rank

  • Ranking in all databases: No. 0
  • Ranking in category/categories:
    • Gene genome and annotation: No. 0
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of circAtlas.

Word cloud

Related Database

Cited

Citing

Record metadata

  • Created on: 2019-03-22
    • ***ina@***c.cn [2019-03-22]
    • ***d@***c.cn [2019-03-22]
    • ***ina@***c.cn [2019-03-22]
    • ***ina@***c.cn [2019-03-22]

Community reviews 0 stars (0 reviews)

Data
quality & quantity
Content
organization & presentation
System
accessibility & reliability
Reviewed by